Bawazeer Ahmed M, Raffa Lina H
Department of Ophthalmology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Oman J Ophthalmol. 2011 Sep;4(3):139-41. doi: 10.4103/0974-620X.91271.
Our objective is to report a case of bilateral nodular scleritis in a 34-year-old patient, resistant to steroids and traditional disease modifying anti-rheumatic drugs, who was successfully treated with subcutaneous injections of 40 mg adalimumab. Adalimumab resulted in rapid control of scleritis in both eyes within 3 months with no recurrence over 5 years of follow-up. No side effects were reported during treatment.Although a large prospective study and a longer follow-up are required to reach a conclusive result, adalimumab has a potential role in the treatment of the above condition with the control of inflammation.
我们的目的是报告一例34岁双侧结节性巩膜炎患者,该患者对类固醇和传统抗风湿病情改善药物耐药,经皮下注射40mg阿达木单抗成功治疗。阿达木单抗在3个月内迅速控制了双眼巩膜炎,随访5年无复发。治疗期间未报告副作用。尽管需要大规模前瞻性研究和更长时间的随访才能得出确凿结果,但阿达木单抗在控制炎症治疗上述病症方面具有潜在作用。