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阿达木单抗治疗复发性特发性双侧结节性巩膜炎。

Adalimumab in the treatment of recurrent idiopathic bilateral nodular scleritis.

作者信息

Bawazeer Ahmed M, Raffa Lina H

机构信息

Department of Ophthalmology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.

出版信息

Oman J Ophthalmol. 2011 Sep;4(3):139-41. doi: 10.4103/0974-620X.91271.

Abstract

Our objective is to report a case of bilateral nodular scleritis in a 34-year-old patient, resistant to steroids and traditional disease modifying anti-rheumatic drugs, who was successfully treated with subcutaneous injections of 40 mg adalimumab. Adalimumab resulted in rapid control of scleritis in both eyes within 3 months with no recurrence over 5 years of follow-up. No side effects were reported during treatment.Although a large prospective study and a longer follow-up are required to reach a conclusive result, adalimumab has a potential role in the treatment of the above condition with the control of inflammation.

摘要

我们的目的是报告一例34岁双侧结节性巩膜炎患者,该患者对类固醇和传统抗风湿病情改善药物耐药,经皮下注射40mg阿达木单抗成功治疗。阿达木单抗在3个月内迅速控制了双眼巩膜炎,随访5年无复发。治疗期间未报告副作用。尽管需要大规模前瞻性研究和更长时间的随访才能得出确凿结果,但阿达木单抗在控制炎症治疗上述病症方面具有潜在作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/490d/3263168/638bd9588aaa/OJO-4-139-g001.jpg

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