Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Clin Transplant. 2012 Jul-Aug;26(4):577-80. doi: 10.1111/j.1399-0012.2011.01592.x. Epub 2012 Jan 26.
We recently published the high frequency of perceived hearing impairment in adults after orthotopic liver transplantation (OLT). To obtain objective data in addition to the questionnaires, audiometric data of 70 patients' post-OLT were analyzed.
Hearing tests were obtained from 70 patients who were in follow-up 6.5 ± 4.3 yr after OLT. Thirty-eight of these patients (53%) reported the development of a hearing problem post-OLT, while 14 patients already noticed hearing loss prior to OLT (21%). Eighteen patients did not report any hearing problems (26%).
Audiometry was within the normal range only in five patients (7%). Signs of mild or moderate hearing loss were found in 12 (17%) and 28 patients (40%), respectively. In 25 patients, audiometry revealed even severe hearing loss (36%). In 86% of patients, hearing loss was bilateral affecting all frequency areas in 63%. Of the 18 patients without subjective hearing impairment, moderate or severe hearing loss was found in 50% of audiometries. Mean maximal hearing loss was -62 ± 30 dB with worse results in patients reporting hearing problems (p < 0.03).
We confirmed the high incidence of reported hearing loss in adults post-OLT by objective audiometric data. Pathological hearing tests were even found in many patients without perception of hearing impairment.
我们最近发表了成人原位肝移植(OLT)后听力障碍的高发病率。为了除问卷外获得客观数据,分析了 70 例 OLT 后患者的听力数据。
对 70 例随访患者进行了听力测试,OLT 后 6.5±4.3 年。其中 38 例(53%)报告 OLT 后出现听力问题,14 例(21%)在 OLT 前已发现听力损失。18 例患者未报告任何听力问题(26%)。
仅 5 例(7%)听力检查在正常范围内。12 例(17%)和 28 例(40%)分别有轻度或中度听力损失。25 例患者听力检查显示甚至严重听力损失(36%)。86%的患者听力损失为双侧,63%的患者所有频率区均受累。在 18 例无主观听力障碍的患者中,50%的听力检查发现中度或重度听力损失。最大听力损失平均为-62±30dB,报告听力问题的患者结果更差(p<0.03)。
我们通过客观听力数据证实了成人 OLT 后报告听力损失的高发病率。即使在没有听力障碍感知的许多患者中,也发现了病理性听力测试。