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腰椎间盘疾病住院的风险因素。

Risk factors for hospitalization due to lumbar disc disease.

机构信息

Department of Public Health & Clinical Medicine, Occupational and Environmental Medicine, Umeå University, Umeå, Sweden.

出版信息

Spine (Phila Pa 1976). 2012 Jul 1;37(15):1334-9. doi: 10.1097/BRS.0b013e31824b5464.

Abstract

STUDY DESIGN

Prospective cohort study.

OBJECTIVE

To study biomechanical factors in relation to symptomatic lumbar disc disease.

SUMMARY OF BACKGROUND DATA

The importance of biomechanical factors in lumbar disc disease has been questioned in the past decade and knowledge from large prospective studies is lacking.

METHODS

The study basis is a cohort of 263,529 Swedish construction workers who participated in a national occupational health surveillance program from 1971 until 1992. The workers' job title, smoking habits, body weight, height, and age were registered at the examinations. The occurrence of hospitalization due to lumbar disc disease from January 1, 1987, until December 31, 2003, was collected from a linkage with the Swedish Hospital Discharge Register.

RESULTS

There was an increased risk for hospitalization due to lumbar disc disease for several occupational groups compared with white-collar workers and foremen. Occupational groups with high biomechanical loads had the highest risks, for example, the relative risk for concrete workers was 1.55 (95% confidence interval [CI], 1.29-1.87). A taller stature was consistently associated with an increased risk. The relative risk for a man of 190- to 199-cm height was 1.55 (95% CI, 1.30-1.86) compared with a man being 170- to 179-cm height. Body weight and smoking were also risk factors, but weaker than height. Workers in the age span of 30 to 39 years had the highest relative risk (RR = 1.87; 95% CI, 1.58-2.23) compared with those aged 20 to 29 years, whereas men aged 60 to 65 years had a lower risk (RR = 0.86; 95% CI, 0.68-1.09).

CONCLUSION

This study indicates that factors increasing the load on the lumbar spine are associated with hospitalization for lumbar disc disease. Occupational biomechanical factors seem to be important, and a taller stature was consistently associated with an increased risk.

摘要

研究设计

前瞻性队列研究。

目的

研究与症状性腰椎间盘疾病相关的生物力学因素。

背景资料概要

在过去十年中,腰椎间盘疾病的生物力学因素的重要性受到了质疑,而且缺乏来自大型前瞻性研究的知识。

方法

该研究的基础是一个由 263529 名瑞典建筑工人组成的队列,他们参加了 1971 年至 1992 年的国家职业健康监测计划。在检查时记录了工人的职称、吸烟习惯、体重、身高和年龄。从与瑞典医院出院登记处的链接中收集了 1987 年 1 月 1 日至 2003 年 12 月 31 日因腰椎间盘疾病住院的情况。

结果

与白领和工头相比,几个职业群体因腰椎间盘疾病住院的风险增加。职业群体的生物力学负荷较高,风险最高,例如,混凝土工人的相对风险为 1.55(95%置信区间[CI],1.29-1.87)。身高较高与风险增加一致相关。身高 190-199cm 的男性的相对风险为 1.55(95%CI,1.30-1.86),而身高 170-179cm 的男性的相对风险为 1.55(95%CI,1.30-1.86)。体重和吸烟也是危险因素,但比身高弱。与 20-29 岁年龄组相比,30-39 岁年龄组的相对风险最高(RR=1.87;95%CI,1.58-2.23),而 60-65 岁的男性风险较低(RR=0.86;95%CI,0.68-1.09)。

结论

本研究表明,增加腰椎负荷的因素与腰椎间盘疾病住院有关。职业生物力学因素似乎很重要,身高较高与风险增加一致相关。

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