Schroeder U, Gebhard M P E, Wollenberg B
Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde & Plastische Operationen, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23583, Lübeck, Deutschland.
HNO. 2012 Jan;60(1):41-3. doi: 10.1007/s00106-011-2424-7.
Although the glottis is amenable to chemotherapy, currently most lesions from stage I laryngeal dysplasia up to carcinoma in situ are excised. This literature review presents selected molecular biological aspects especially in relation to dysplasia of the larynx and its therapy, as well as currently preferred biomarkers for chemotherapeutic prevention of laryngeal dysplasia.
虽然声门对化疗敏感,但目前从I期喉发育异常到原位癌的大多数病变都采用手术切除。这篇文献综述介绍了选定的分子生物学方面,特别是与喉发育异常及其治疗相关的内容,以及目前用于化疗预防喉发育异常的首选生物标志物。