在甲胺的化学氧化过程中形成偶氮甲烷，一种结肠癌致癌物。
The formation of azoxymethane, a colon carcinogen, during the chemical oxidation of methylamine.
机构信息
Division of Molecular Biology and Pharmacology, Naylor Dana Institute for Disease Prevention, American Health Foundation, Valhalla, NY 10595, USA.
出版信息
Carcinogenesis. 1980 Jan;1(1):57-60. doi: 10.1093/carcin/1.1.57.
PMID:22282981
Abstract
Simple chemical oxidation of methylamine in aqueous solution or in methanol leads to the formation of significant amounts of azoxymethane, a strong carcinogen in rodents. Methods, including high pressure liquid chromatography, differential pulse polarography and gas chromatography-mass spectrometry, used for the identification of the carcinogen, are described.
摘要
简单的水溶液或甲醇中一甲胺的化学氧化会导致大量偶氮甲烷的形成，而偶氮甲烷是一种强烈的啮齿动物致癌物。本文描述了用于鉴定致癌物的方法，包括高效液相色谱法、差示脉冲极谱法和气相色谱-质谱法。
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