Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.
Int J Radiat Oncol Biol Phys. 2012 Mar 1;82(3):1047-57. doi: 10.1016/j.ijrobp.2011.07.020.
Over the past decade, there has been an increasing use of radiotherapy (RT) for the treatment of liver metastases. Most often, ablative doses are delivered to focal liver metastases with the goal of local control and ultimately improving survival. In contrast, low-dose whole-liver RT may be used for the palliation of symptomatic diffuse metastases. This review examines the available clinical data for both approaches. The review found that RT is effective both for local ablation of focal liver metastases and for palliation of patients with symptomatic liver metastases. However, there is a lack of a high level of evidence from randomized clinical trials.
在过去的十年中，放射治疗（RT）在肝脏转移瘤的治疗中得到了越来越多的应用。大多数情况下，采用消融剂量对肝内局灶性转移灶进行治疗，以达到局部控制的目的，并最终改善生存。相反，低剂量全肝 RT 可能用于缓解症状性弥漫性转移。本综述检查了这两种方法的现有临床数据。综述发现，RT 对局部消融肝内局灶性转移灶和缓解有症状的肝转移患者均有效。然而，随机临床试验缺乏高级别的证据。
