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血小板功能检测在小动物临床实践中的评估及临床应用

Evaluation and clinical application of platelet function testing in small animal practice.

作者信息

Christopherson Pete W, Spangler Elizabeth A, Boudreaux Mary K

机构信息

Department of Pathobiology, Auburn University College of Veterinary Medicine, 166 Greene Hall, Auburn, AL 36849, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2012 Jan;42(1):173-88. doi: 10.1016/j.cvsm.2011.09.013. Epub 2011 Nov 29.

Abstract

Tests that evaluate many aspects of platelet function have been applied in both human and veterinary medicine for the monitoring of treatment with platelet function inhibitors and for detection of platelet function abnormalities (inherited or acquired). Interspecies variation in the response to various platelet agonists is an important consideration when methods that have been developed for people are applied in other species. At the present time, many of these assays are not readily available in standard veterinary practice. Advanced platelet function testing for veterinary patients is offered at select academic institutions. Discussion with a specialist is recommended when considering the use of these tests, and the relative strengths and limitations of each assay should be considered in the interpretation of test results.

摘要

评估血小板功能多个方面的检测方法已应用于人类和兽医学,用于监测血小板功能抑制剂的治疗效果以及检测血小板功能异常(遗传性或获得性)。当将针对人类开发的方法应用于其他物种时,对各种血小板激动剂的反应存在种间差异是一个重要的考虑因素。目前,许多此类检测方法在标准兽医实践中并不容易获得。部分学术机构可为兽医患者提供先进的血小板功能检测。在考虑使用这些检测方法时,建议与专家进行讨论,并且在解释检测结果时应考虑每种检测方法的相对优势和局限性。

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