Department of Chemistry, Bengal Engineering and Science University, Shibpur, Howrah 711103, India.
Org Biomol Chem. 2012 Mar 21;10(11):2231-6. doi: 10.1039/c2ob06792g. Epub 2012 Jan 27.
A carbazole-thiosemicarbazone-Hg(2+) ensemble-based fluorogenic probe for detection of iodide in aqueous media is reported. The first fluorescent sensor for iodide anions was constructed based on the displacement approach. An 'ensemble' is able to selectively sense iodide over other anions followed by the release of 9-(butane-1-yl)-9H-carbazole-3,6-dihydrazinecarbothioamide to give a remarkable change of fluorescence turn-on signal at pH 7.4 under aqueous media. The practical use of an 'ensemble' was demonstrated by its application to the detection of iodide in the living cells.
报道了一种基于咔唑硫代半卡巴腙-Hg(2+)配合物的荧光探针，用于检测水相中的碘化物。基于取代法构建了第一个用于碘阴离子的荧光传感器。“配合物”能够选择性地识别碘化物而不是其他阴离子，随后释放 9-(正丁基)-9H-咔唑-3,6-二腙甲硫酰胺，在水相介质中 pH 值为 7.4 时会产生显著的荧光开启信号变化。通过将“配合物”应用于活细胞中碘化物的检测，证明了其实际用途。
