Hino Haruaki, Murakawa Tomohiro, Nagayama Kazuhiro, Nakajima Jun
Department of Thoracic Surgery, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Interact Cardiovasc Thorac Surg. 2012 May;14(5):655-7. doi: 10.1093/icvts/ivs004. Epub 2012 Jan 27.
A 77-year old male patient was admitted for the treatment of a thoracic aortic aneurysm (TAA) and primary lung cancer. A saccular aneurysm, 4.8 cm in diameter, located in the proximal segment of the descending thoracic aorta and a pulmonary tumour, 3 cm in diameter, located at the right lower lobe, with lymph node swelling, were detected simultaneously. First, a thoracic endovascular aortic repair (TEVAR) was performed for TAA, and then 45 days later, a lobectomy and radical lymph node dissection by open thoracotomy were performed safely for primary lung cancer. The postoperative course was complicated by a bronchopleural fistula (BPF). Massive necrotic changes to the bronchial stump and the intercostal muscle flap were observed during an open window thoracotomy. Both the chronic use of corticosteroids and TEVAR may have been among the predisposing factors for the occurrence of the fistula. The patient died as a result of respiratory failure 68 days after the lobectomy. This is a first case report of a BPF after a staged operation of TEVAR and major lung surgery. We reviewed and discussed the surgical strategy and timing for both the primary lung cancer and the thoracic aortic aneurysm.
一名77岁男性患者因胸主动脉瘤(TAA)和原发性肺癌入院治疗。同时发现一个直径4.8厘米的囊状动脉瘤,位于胸降主动脉近端,以及一个直径3厘米的肺肿瘤,位于右下叶,并伴有淋巴结肿大。首先,对TAA进行了胸主动脉腔内修复术(TEVAR),然后在45天后,通过开胸手术安全地进行了肺叶切除术和根治性淋巴结清扫术以治疗原发性肺癌。术后病程出现了支气管胸膜瘘(BPF)并发症。在开胸开窗手术中观察到支气管残端和肋间肌瓣出现大量坏死改变。长期使用皮质类固醇和TEVAR可能都是瘘管发生的诱发因素。患者在肺叶切除术后68天因呼吸衰竭死亡。这是首例关于TEVAR分期手术和大型肺部手术后发生BPF的病例报告。我们回顾并讨论了原发性肺癌和胸主动脉瘤的手术策略及时机。