与肾细胞癌相关的遗传综合征：综述
Genetic syndromes associated with renal cell carcinoma: a review.
作者信息
Azeem Katerina, Kollarova Helena, Horakova Dagmar, Magnuskova Silvie, Janout Vladimir
机构信息
Department of Preventive Medicine, Palacky University Olomouc, Czech Republic.
出版信息
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2011 Sep;155(3):231-8. doi: 10.5507/bp.2011.029.
AIMS
A review of recent knowledge on heredital syndromes related to renal cell carcinoma.
METHODS
Aim of this review was to summarize the recent knowledge of genetic syndromes associated with renal cell carcinoma.
RESULTS
Summary of incidence and factors modulating risk of hereditary renal cell carcinoma development.
CONCLUSIONS
Hereditary forms of RCC are relatively rare. Their study is beneficial in many ways. In individuals at a higher risk of a hereditary syndrome, the knowledge of hereditary forms may help to significantly decrease the impact of the hereditary disease. In the general population, knowledge acquired by the study of hereditary forms of RCC may in the future contribute to both diagnosis and treatment of sporadic tumours.
目的
综述与肾细胞癌相关的遗传性综合征的最新知识。
方法
本综述的目的是总结与肾细胞癌相关的遗传综合征的最新知识。
结果
遗传性肾细胞癌发生风险的发生率及调节因素总结。
结论
遗传性肾细胞癌相对少见。对其进行研究在很多方面都有益处。对于有较高遗传性综合征风险的个体，了解遗传性形式可能有助于显著降低遗传性疾病的影响。在普通人群中，通过研究遗传性肾细胞癌所获得的知识未来可能有助于散发性肿瘤的诊断和治疗。
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