Department of Otolaryngology-Head and Neck Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ, USA.
Int Forum Allergy Rhinol. 2011 Sep-Oct;1(5):379-81. doi: 10.1002/alr.20061. Epub 2011 May 9.
Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) is a recognized entity that is increasingly responsible for skin and soft tissue infections. However, it is not the usual pathogen isolated in nasal vestibular abscess.
We present a series of 13 consecutive patients presenting to a tertiary care center with nasal vestibular abscess over a 2.5-year period.
All abscesses were cultured and 100% (13/13) grew S. aureus. Of the S. aureus isolates, 92% (12/13) were MRSA. Antibiotic susceptibilities of the MRSA isolates were as follows: 100% were susceptible to rifampin, trimethoprim-sulfamethoxazole, and tetracycline, 75% to clindamycin, 58% to fluoroquinolones, and 17% to erythromycin.
MRSA is an important pathogen in the community. It is therefore critical to appreciate its potential predominance in nasal vestibular abscess. Clinicians should obtain cultures, modify antibiotic therapy as warranted, and initiate empiric therapy to include MRSA coverage for nasal vestibular abscess.
社区获得性耐甲氧西林金黄色葡萄球菌(MRSA)是一种公认的病原体,它越来越多地导致皮肤和软组织感染。然而,它并不是鼻腔前庭脓肿中常见的分离病原体。
我们报告了在 2.5 年期间,在一家三级护理中心连续就诊的 13 例鼻腔前庭脓肿患者。
所有脓肿均进行了培养,100%(13/13)的培养物中生长出金黄色葡萄球菌。在金黄色葡萄球菌分离株中,92%(12/13)为耐甲氧西林金黄色葡萄球菌。耐甲氧西林金黄色葡萄球菌分离株的抗生素药敏性如下:利福平、复方磺胺甲噁唑和四环素的敏感性为 100%,克林霉素为 75%,氟喹诺酮类为 58%,红霉素为 17%。
MRSA 是社区中的一种重要病原体。因此,必须认识到它在鼻腔前庭脓肿中的潜在优势。临床医生应获取培养物,根据需要调整抗生素治疗,并开始经验性治疗,包括鼻腔前庭脓肿的 MRSA 覆盖。