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活体供肾者的结局。

Outcome of the living kidney donor.

机构信息

Department of Nephrology, Dialysis, Transplantation, University of Liêge, CHU Sart Tilman, Liêge, Belgium.

出版信息

Nephrol Dial Transplant. 2012 Jan;27(1):41-50. doi: 10.1093/ndt/gfr669.

DOI:10.1093/ndt/gfr669
PMID:22287701
Abstract

Renal transplantation from living kidney donors is still relatively marginal in most of the European countries. However, this source of kidney grafts may help to overcome in part the organ donor shortage of cadaveric donors. The living donor strategy implies correct and objective information about donation risks and completely free acceptance of the living candidate of the donation. In this paper, we reviewed the consequences of kidney donation on the living donor health, considering very short term (linked to the surgery), short term (effect of nephrectomy on glomerular filtration rate) and long term (risk of mortality, chronic kidney disease, proteinuria and hypertension) consequences of kidney donation.

摘要

在大多数欧洲国家,活体供肾移植仍然相对较少。然而,这种肾脏移植物来源可能有助于部分克服尸体供者器官短缺的问题。活体供者策略意味着需要提供关于捐赠风险的正确和客观的信息,并让活体供者完全自由地接受捐赠。本文回顾了肾脏捐献对活体供者健康的影响,考虑了非常短期(与手术相关)、短期(肾切除对肾小球滤过率的影响)和长期(死亡率、慢性肾脏病、蛋白尿和高血压风险)的后果。

相似文献

1
Outcome of the living kidney donor.活体供肾者的结局。
Nephrol Dial Transplant. 2012 Jan;27(1):41-50. doi: 10.1093/ndt/gfr669.
2
Post-nephrectomy development of renal function in living kidney donors: a cross-sectional retrospective study.活体肾捐献者肾切除术后肾功能的发展:一项横断面回顾性研究。
Nephrol Dial Transplant. 2011 Jul;26(7):2377-81. doi: 10.1093/ndt/gfr161. Epub 2011 Mar 31.
3
[Quality of life of living kidney donor: a national report].[活体肾供体的生活质量:一份全国性报告]
Nephrol Ther. 2011 Jul;7 Suppl 1:S1-39. doi: 10.1016/S1769-7255(11)70007-4.
4
The long-term consequences of living-related or unrelated kidney donation.活体亲属或非亲属肾捐赠的长期后果。
Nephrol Dial Transplant. 2004 Jul;19 Suppl 4:iv45-7. doi: 10.1093/ndt/gfh1041.
5
The assessment of residual kidney function after living donor nephrectomy.活体供肾切除术后残余肾功能的评估。
Transplant Proc. 2009 Jan-Feb;41(1):91-2. doi: 10.1016/j.transproceed.2008.08.160.
6
Long-term outcomes of living kidney donors: a single centre experience of 29 years.活体肾捐献者的长期预后:29 年单中心经验
Nephrology (Carlton). 2012 Jan;17(1):85-8. doi: 10.1111/j.1440-1797.2011.01524.x.
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Influence of the kidney histology at the time of donation on long term kidney function in living kidney donors.捐赠时肾脏组织学对活体肾捐赠者长期肾功能的影响。
Transplant Proc. 2005 Oct;37(8):3351-3. doi: 10.1016/j.transproceed.2005.09.095.
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Living donor kidney transplants: personal reflections.活体供肾移植:个人反思
Transplant Proc. 2005 Nov;37(9):3592-4. doi: 10.1016/j.transproceed.2005.10.079.
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Long-term outcomes of living kidney donors over the past 28 years in a single center in Taiwan.台湾某单一中心过去28年活体肾供者的长期结局
Transplant Proc. 2012 Jan;44(1):39-42. doi: 10.1016/j.transproceed.2011.12.024.
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Why should we implement living donation in renal transplantation?我们为什么要在肾移植中实施活体捐赠?
Clin Nephrol. 2000 Apr;53(4):suppl 55-63.

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Personalized prediction model generated with machine learning for kidney function one year after living kidney donation.通过机器学习生成的活体肾移植术后一年肾功能个性化预测模型。
Sci Rep. 2025 Jul 1;15(1):20752. doi: 10.1038/s41598-025-02879-y.
2
The utility of split function testing in determining recovery of glomerular filtration rate after living kidney donation: a cohort study.活体肾捐献后采用分段功能测试评估肾小球滤过率恢复情况的效用:一项队列研究。
BMC Nephrol. 2025 Jan 18;26(1):31. doi: 10.1186/s12882-025-03956-0.
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Renal Outcomes With Renin-Angiotensin System Blockers After Unilateral Nephrectomy.
单侧肾切除术后肾素-血管紧张素系统阻滞剂的肾脏结局
Kidney Int Rep. 2024 Oct 10;10(1):184-196. doi: 10.1016/j.ekir.2024.09.022. eCollection 2025 Jan.
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The Development of a Predictive Model for Postoperative Renal Function in Living Kidney-Transplant Donors.活体肾移植供者术后肾功能预测模型的开发
J Clin Med. 2024 Nov 23;13(23):7090. doi: 10.3390/jcm13237090.
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Urinary Dickkopf 3 Is Not an Independent Risk Factor in a Cohort of Kidney Transplant Recipients and Living Donors.尿 Dickkopf 3 不是肾移植受者和活体供者队列中的独立危险因素。
Int J Mol Sci. 2024 May 15;25(10):5376. doi: 10.3390/ijms25105376.
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Association of Pre- and Post-Donation Renal Function with Midterm Estimated Glomerular Filtration Rate in Living Kidney Donors: A Retrospective Study.供者移植前、后肾功能与活体肾移植受者中期估算肾小球滤过率的相关性:一项回顾性研究。
Yonsei Med J. 2023 Mar;64(3):221-227. doi: 10.3349/ymj.2022.0541.
7
Comparison of CT volumetry versus nuclear renography for predicting remaining kidney function after uninephrectomy in living kidney donors.CT 容积测量与核肾图对活体供肾者肾切除术后剩余肾功能预测的比较。
Sci Rep. 2022 Mar 24;12(1):5144. doi: 10.1038/s41598-022-09187-9.
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Glomerular Biomechanical Stress and Lipid Mediators during Cellular Changes Leading to Chronic Kidney Disease.导致慢性肾病的细胞变化过程中的肾小球生物力学应激与脂质介质
Biomedicines. 2022 Feb 9;10(2):407. doi: 10.3390/biomedicines10020407.
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Barriers to the donation of living kidneys for kidney transplantation.活体肾脏捐献用于肾脏移植的障碍。
Sci Rep. 2022 Feb 14;12(1):2397. doi: 10.1038/s41598-022-06452-9.
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Prevalence, Mechanisms, Treatment, and Complications of Hypertension Postliving Kidney Donation.活体肾移植后高血压的患病率、机制、治疗和并发症。
Biomed Res Int. 2021 Feb 4;2021:5460672. doi: 10.1155/2021/5460672. eCollection 2021.