Dipartimento di Scienze per la Salute della Donna e del Bambino, Sezione di Ginecologia e Ostetricia, Policlinico di Careggi, Via Morgagni 85, 50134, Firenze, Italy.
Anticancer Res. 2012 Feb;32(2):707-12.
To compare minilaparotomic and vaginal surgery in selected obese patients with early-stage endometrial cancer at high surgical risk.
Data of 37 consecutive class II-III obese patients submitted to minilaparotomic surgery were retrospectively reviewed. Thirty-seven women matched for demographic characteristics, BMI and stage of disease submitted to vaginal surgery in the same period comprised the control group.
No difference was observed concerning intra- and postoperative data among the two groups. The patients who were submitted to general anesthesia exhibited a larger use of supplemental drugs for pain control (p>0.01), a higher incidence of thromboembolic events (p>0.005) and a longer hospitalization (p>0.02). No statistical difference was observed in terms of pattern of recurrence, disease-free survival and overall survival between the two groups of patients.
Obese patients with endometrial cancer unfit for vaginal surgery can be safely managed through mini-laparotomy with the same surgical and oncological outcomes.
比较腹腔镜辅助小切口手术与阴道手术在高手术风险的特定肥胖患者中治疗早期子宫内膜癌的效果。
回顾性分析了 37 例连续的 II-III 级肥胖且接受腹腔镜辅助小切口手术的患者的数据。同期，为了匹配年龄、体重指数和疾病分期，选择了 37 例接受阴道手术的肥胖患者作为对照组。
两组患者的术中及术后数据无差异。接受全身麻醉的患者在疼痛控制辅助药物的使用（p＞0.01）、血栓栓塞事件（p＞0.005）的发生率以及住院时间（p＞0.02）上均有更高的表现。两组患者的复发模式、无病生存率和总生存率无统计学差异。
对于不能接受阴道手术的肥胖子宫内膜癌患者，可以通过腹腔镜辅助小切口手术安全地进行治疗，获得相同的手术和肿瘤学结果。
