尼日利亚阿布贾联邦首都地区（FCT）中学生对镰状细胞病的认知与态度
Knowledge and attitudes of secondary school students in Federal Capital Territory (FCT), Abuja, Nigeria towards sickle cell disease.
作者信息
Owolabi Rotimi S, Alabi Peter, Olusoji Daniel, Ajayi Samuel, Otu Theresa, Ogundiran Adeniyi
机构信息
HIV/AIDS Unit, Department of Medicine, University of Abuja Teaching Hospital, Gwagwalada, Abuja, Nigeria.
出版信息
Niger J Med. 2011 Oct-Dec;20(4):479-85.
BACKGROUND
This study was conducted among Secondary School Students in Federal Capital Territory (FCT),Abuja Nigeria, between May and June 2010 to determine the knowledge and attitudes of the students towards Sickle Cell Disease (SCD).
METHODS
The study was a cross-sectional study carried out on 600 students from 8 secondary schools located within (FCT). A multistage sampling method was used for selection of the study population. Data was collected with the aid of a pretested self-administered questionnaire and analyzed with EPI-INFO 2008.
RESULTS
The age of respondents ranged from 9 to 26 years with the mean age of 15.16 (SD = 2.13). The modal age of the respondents was 10-19 years (97.8%). The male: female ratio was 1.01:1. A large number of respondents' fathers (80.7%) and mothers (70.2%) respectively, had at least secondary school education. Majority (81.8%) of the respondents claimed to have heard about sickle cell disease (SCD) but only 38.0% of them knew the cause of SCD. Slightly less than half, 292 (48.7%) of the respondents knew their genotype. Of the 292 respondents that knew their genotype, 206 (70.5%) were AA, 50 (17.1%) were AS,14 (4.8%), SS, 11 (3.8%)AC, 5 (1.7%) SC, 4 (1.4%) CC, 2 (0.7%) other types of genotype. Only 46.2% and 36.8% of them respectively, correctly identified that pre-marital genotype testing and avoidance of marriage between two persons with haemoglobin S genotype as means of preventing further spread of SCD. Factors found to be significantly associated with the knowledge of respondents' genotype were; age = 15 years, respondents' mothers' educational status, being taught about SCD in school, ever seeing somebody suffering from SCD complication, losing a relative to SCD, being in senior secondary school class and knowing the cause of SCD.
CONCLUSION
This study shows that majority of the respondents did not know their genotype ,and their knowledge about the cause and prevention of SCD was poor.
背景
2010年5月至6月，在尼日利亚阿布贾联邦首都区的中学生中开展了本研究，以确定学生对镰状细胞病（SCD）的知识和态度。
方法
本研究为横断面研究，对来自联邦首都区8所中学的600名学生进行。采用多阶段抽样方法选择研究人群。借助预先测试的自填问卷收集数据，并使用EPI-INFO 2008进行分析。
结果
受访者年龄在9至26岁之间，平均年龄为15.16岁（标准差=2.13）。受访者的众数年龄为10 - 19岁（97.8%）。男女比例为1.01:1。大量受访者的父亲（80.7%）和母亲（70.2%）分别至少接受过中学教育。大多数（81.8%）受访者声称听说过镰状细胞病（SCD），但其中只有38.0%知道SCD的病因。略少于一半，即292名（48.7%）受访者知道自己的基因型。在这292名知道自己基因型的受访者中，206名（70.5%）为AA型，50名（17.1%）为AS型，14名（4.8%）为SS型，11名（3.8%）为AC型，5名（1.7%）为SC型，4名（1.4%）为CC型，2名（0.7%）为其他类型的基因型。他们中分别只有46.2%和36.8%正确地认识到婚前基因型检测以及避免血红蛋白S基因型的两人结婚是预防SCD进一步传播的方法。发现与受访者基因型知识显著相关的因素有：年龄=15岁、受访者母亲的教育程度、在学校接受过SCD教育、曾见过有人患有SCD并发症、有亲属因SCD去世、就读于高中班级以及知道SCD的病因。
结论
本研究表明，大多数受访者不知道自己的基因型，并且他们对SCD的病因和预防知识了解不足。
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