Department of Human Development and Applied Psychology, University of Toronto Toronto Western Research Institute, Toronto, ON, Canada.
Genes Brain Behav. 2012 Apr;11(3):262-8. doi: 10.1111/j.1601-183X.2012.00769.x. Epub 2012 Mar 1.
This study examined associations among maternal sensitivity, mothers' early adversity and the Arginine Vasopressin 1a Receptor (AVPR1A) gene. Early adversity in mothers' background has been found to be associated with lower maternal sensitivity. Animal literature suggests that variation in the AVPR1A gene is associated with parenting quality. The goal of the study was to examine the role of the AVPR1A gene in maternal sensitivity, especially under conditions of high early adversity. Participants included 151 Caucasian women from a community sample. The women were videotaped in their home while interacting separately with two of their children (target child = 18 months, older sibling <6 years). Evidence was found for an association between the AVPR1A gene and maternal sensitivity. Mothers with two copies of the long RS3 alleles were less sensitive than mothers with one or zero copies of the long alleles. This association was strongest under conditions of high maternal early adversity.
本研究考察了母亲敏感性、母亲早期逆境与精氨酸加压素 1a 受体 (AVPR1A) 基因之间的关联。研究发现，母亲背景中的早期逆境与较低的母亲敏感性有关。动物文献表明，AVPR1A 基因的变异与育儿质量有关。该研究的目的是探讨 AVPR1A 基因在母亲敏感性中的作用，特别是在高早期逆境的情况下。参与者包括来自社区样本的 151 名白种人女性。这些女性在自己的家中与两个孩子（目标孩子=18 个月，年龄较大的兄弟姐妹<6 岁）分别互动时被录像。有证据表明 AVPR1A 基因与母亲敏感性有关。携带两个长 RS3 等位基因的母亲比携带一个或零个长等位基因的母亲敏感性差。这种关联在母亲早期逆境较高的情况下最强。
