Apiliogullari B, Sunam G S, Ceran S, Koc H
Department of Thoracic Surgery, Selcuk University, Meram Medical Faculty, Beysehir Cad. 42090 Konya, Turkey.
J Int Med Res. 2011;39(6):2436-40. doi: 10.1177/147323001103900645.
Pneumothorax progresses quickly in newborns and can lead to death. This study collected data prospectively over a 2-year period on risk factors, clinical course and prognostic factors of newborn cases diagnosed and treated for pneumothorax. Thirty patients were evaluated for risk factors including concurrent disease, method and duration of chest drainage, oxygen saturation and mechanical ventilation. Pneumothorax developed mostly in male and mature infants during the first 48 h following birth; risk factors included concurrent respiratory distress syndrome and meconium aspiration. Mechanical ventilation was undertaken in 18 (60%) of the patients. Closed-tube drainage was used in 28 (93%) of the patients. Nine out of 10 patients (90%) whose oxygen saturation remained < 90% died. Thus, pneumothorax may develop during the neonatal period, especially in the presence of risk factors, and neonates with < 90% oxygen saturation, despite treatment, have a high mortality rate.
气胸在新生儿中进展迅速,可导致死亡。本研究前瞻性收集了2年期间诊断并治疗气胸的新生儿病例的危险因素、临床病程及预后因素的数据。对30例患者评估了危险因素,包括合并疾病、胸腔引流方法及持续时间、血氧饱和度和机械通气情况。气胸大多在出生后48小时内发生于男性和足月儿;危险因素包括合并呼吸窘迫综合征和胎粪吸入。18例(60%)患者接受了机械通气。28例(93%)患者采用了闭式引流。血氧饱和度持续<90%的患者中,10例有9例(90%)死亡。因此,气胸可能在新生儿期发生,尤其是存在危险因素时,且血氧饱和度<90%的新生儿,即便接受治疗,死亡率仍很高。