Neonatal Intensive Care Unit, Brenner Children's Hospital, Winston Salem, NC, USA.
J Perinatol. 2012 Feb;32(2):150-2. doi: 10.1038/jp.2011.105.
SimplyThick(®)(ST) has been safely used as a thickener to treat adults who have dysphagia, but the safety of this product has not been studied in premature infants. Xanthan gum is the ingredient in ST that results in thickening and also is an effective laxative. We recently began using ST to treat premature infants with dysphagia and/or gastroesophageal reflux. We describe three cases of premature infants who developed necrotizing enterocolitis (NEC) after they were fed ST. Unlike classic NEC, all three cases presented with late-onset colonic NEC.
SimplyThick(®)(ST) 已被安全用作增稠剂来治疗有吞咽困难的成年人，但尚未研究该产品在早产儿中的安全性。黄原胶是 ST 中导致增稠的成分，也是一种有效的泻药。我们最近开始使用 ST 来治疗有吞咽困难和/或胃食管反流的早产儿。我们描述了 3 例在喂食 ST 后发生坏死性小肠结肠炎 (NEC) 的早产儿。与经典的 NEC 不同，所有 3 例均表现为迟发性结肠 NEC。
