中心性浆液性脉络膜视网膜病变光动力疗法后脉络膜厚度的地形学变化：一例光学相干断层扫描病例报告
Topographical Choroidal Thickness Change Following PDT for CSC: An OCT Case Report.
作者信息
Wirostko William J, Nordgren Rick N, Dubis Adam M
机构信息
Department of Ophthalmology, The Eye Institute, Medical College of Wisconsin, 925 North 87th Street, Milwaukee, WI 53226, USA.
出版信息
J Ophthalmol. 2012;2012:347206. doi: 10.1155/2012/347206. Epub 2012 Jan 12.
Purpose. To describe topographical changes in choroidal thickness as measured by optical coherence tomography following photodynamic therapy (PDT) for central serous chorioretinopathy (CSC). Methods. Case report. Results. By 1 month following PDT, mean (SD) choroidal thickness decreased from 562 microns (24) to 424 microns (27) (P < 0.01) at 3 mm temporal to fovea, 483 microns (9) to 341 microns (21) (P < 0.01) at 1.5 mm temporal to fovea, 576 microns (52) to 370 microns (81) (P < 0.01) under the fovea, 442 microns (30) to 331 microns (54) (P < 0.04) at 1.5 mm nasal to fovea, and 274 microns (39) to 171 microns (17) (P < 0.01) at 3 mm nasal to fovea. The Location of greatest choroidal thickness (648 microns) prior to treatment was at point of leakage on fluorescein angiogram (FA). This region decreased to 504 microns following treatment. Conclusion. A decrease in choroidal thickness can be seen following PDT for CSC as far as 3 mm temporal and 3 mm nasal to fovea. The Location of greatest choroidal thickness may be at point of leakage on FA.
目的。描述采用光相干断层扫描测量的中心性浆液性脉络膜视网膜病变（CSC）患者在光动力疗法（PDT）后脉络膜厚度的地形学变化。方法。病例报告。结果。PDT治疗后1个月，在黄斑中心凹颞侧3 mm处，脉络膜平均（标准差）厚度从562微米（24）降至424微米（27）（P<0.01）；在黄斑中心凹颞侧1.5 mm处，从483微米（9）降至341微米（21）（P<0.01）；在黄斑中心凹下，从576微米（52）降至370微米（81）（P<0.01）；在黄斑中心凹鼻侧1.5 mm处，从442微米（30）降至331微米（54）（P<0.04）；在黄斑中心凹鼻侧3 mm处，从274微米（39）降至171微米（17）（P<0.01）。治疗前脉络膜最厚处（648微米）位于荧光素血管造影（FA）的渗漏点。治疗后该区域降至504微米。结论。CSC患者接受PDT治疗后，在黄斑中心凹颞侧3 mm和鼻侧3 mm范围内均可观察到脉络膜厚度降低。脉络膜最厚处可能位于FA的渗漏点。
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