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基于RBL-2H3肥大细胞模型的双黄连注射液过敏患者血清过敏原个体化筛查策略

[Strategy of individualized screening of allergens in serum of patients allergic to Shuanghuanglian injection based on RBL-2H3 mast cell model].

作者信息

Xiao Ying, Zhao Yubin, Xie Yanming

机构信息

Chemistry Department, Shijiazhuang College, Shijiazhuang 050035, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2011 Oct;36(20):2799-802.

Abstract

Screening of allergens in Shuanghuanglian injection is now one of the key and urgently solved problems in assessment on the safety of traditional Chinese medicine injections. In this paper, the author reviewed the improtant progresses in study on Screening of allergens in shuanghuanglian injection. The principle, concrete methods and specific procedure were discussed on the strategy of individualized screening of allergens in serum of patients allergic to Shuanghuanglian injection based on RBL-2H3 mast cell model.

摘要

双黄连注射液过敏原筛查是目前中药注射剂安全性评价中关键且亟待解决的问题之一。本文综述了双黄连注射液过敏原筛查研究的重要进展。基于RBL-2H3肥大细胞模型,对双黄连注射液过敏患者血清过敏原个体化筛查策略的原理、具体方法及详细步骤进行了探讨。

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