Mehlin Christopher
University of Washington, Seattle, Washington, USA.
Curr Protoc Pharmacol. 2004 May 1;Chapter 12:Unit 12.7. doi: 10.1002/0471141755.ph1207s24.
Cell adhesion, a critical early step in the inflammatory process, has increasingly become the target of drug discovery efforts. Described in this unit are techniques for measuring inhibitors of VLA-4-mediated adhesion to either VCAM or the connecting segment (CS-1) of fibronectin.
细胞黏附是炎症过程中的一个关键早期步骤，越来越成为药物研发工作的靶点。本单元介绍了用于测量VLA - 4介导的与血管细胞黏附分子（VCAM）或纤连蛋白连接片段（CS - 1）黏附的抑制剂的技术。
