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一项针对老年髋部骨折患者行人工股骨头置换术后并发症的全国性分析。

A national analysis of complications following hemiarthroplasty for hip fracture in older patients.

机构信息

Northumbria Healthcare NHS Foundation Trust, Northumberland, UK.

出版信息

QJM. 2012 May;105(5):455-60. doi: 10.1093/qjmed/hcs004. Epub 2012 Jan 31.

Abstract

BACKGROUND

There is emerging evidence that patients with fractured neck of femur (FNOF) aged >85 years have different demands on a health-care system when compared to younger patients.

AIM

We sought to better quantify this in terms of comorbidity and complication rates.

DESIGN

Retrospective review of national database.

METHODS

Data on all patients who underwent hip hemiarthroplasty for FNOF between January 2005 and December 2008 were extracted from the English hospital episode statistics database.

RESULTS

There were 41 770 patients aged 65-84 years and 35 321 patients aged ≥85 years. The older cohort was less likely to have diabetes, chronic obstructive pulmonary disease and rheumatoid arthritis. However, they exhibited a significantly higher risk of lower respiratory tract infection [odds ratio (OR) = 1.58, 95% confidence interval (CI) 1.50-1.67)], myocardial infarction (OR = 1.67, 1.52-1.83) and acute renal failure (OR = 1.54, 1.40-1.70) within 30 days of surgery with an inpatient mortality risk at 90 days, double that of the younger age group. Length of stay (LoS) was significantly longer in patients >85 years compared to younger patients (median 18 days vs. 15, P < 0.001).

CONCLUSION

Patients aged ≥85 years admitted for FNOF were found to have a lower incidence of major chronic disease but exhibited a greater incidence of acute events following hemiarthroplasty and their LoS was increased. Targeted medical interventions that focus upon this susceptible patient group may help reduce morbidity and improve survival.

摘要

背景

越来越多的证据表明,年龄>85 岁的股骨颈骨折(FNOF)患者与年轻患者相比,对医疗保健系统有不同的需求。

目的

我们旨在通过合并症和并发症发生率来更好地量化这一点。

设计

对国家数据库的回顾性研究。

方法

从英国医院病例统计数据库中提取了 2005 年 1 月至 2008 年 12 月期间所有因 FNOF 接受髋关节半髋关节置换术的患者的数据。

结果

65-84 岁患者队列中有 41770 例,年龄≥85 岁患者队列中有 35321 例。年龄较大的队列中患有糖尿病、慢性阻塞性肺疾病和类风湿性关节炎的可能性较小。然而,他们在术后 30 天内发生下呼吸道感染(优势比[OR]1.58,95%置信区间[CI]1.50-1.67)、心肌梗死(OR1.67,1.52-1.83)和急性肾功能衰竭(OR1.54,1.40-1.70)的风险显著增加,90 天内住院死亡率是年轻年龄组的两倍。>85 岁患者的住院时间(LoS)明显长于年轻患者(中位数 18 天比 15 天,P<0.001)。

结论

因 FNOF 住院的年龄≥85 岁患者的主要慢性疾病发病率较低,但在接受半髋关节置换术后发生急性事件的发生率较高,且他们的 LoS 延长。针对这一易感患者群体的有针对性的医疗干预措施可能有助于降低发病率并提高生存率。

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