UCSF Global Health Sciences, 950 Mee Lane, St Helena, CA 94574, USA.
Br J Haematol. 2012 Mar;156(6):766-9. doi: 10.1111/j.1365-2141.2012.09035.x. Epub 2012 Feb 1.
Denis Burkitt's description of the eponymous lymphoma in 1958 in Uganda, opened up a vast and important field of enquiry in haematology and oncology. His pioneering experiments with chemotherapy demonstrated the possibility of cure, often with a single dose. His geographical explorations showed the tumour to be delimited by climate, suggesting an infectious cause vectored by mosquitoes. His clinical observations furthered the field of cancer immunotherapy. And his collegial, inquisitive nature facilitated the development of an enduring cancer research centre in Kampala. Burkitt's legacy in Uganda has wide-reaching effects that endure not only in Uganda but also throughout the haematology-oncology community to this day.
1958 年,丹尼斯·伯基特(Denis Burkitt)在乌干达对这种命名性淋巴瘤的描述,开辟了血液学和肿瘤学领域一个广阔而重要的研究领域。他对化疗的开创性实验证明了治愈的可能性,通常只需一剂即可。他的地理探索表明,这种肿瘤受气候限制,提示其可能由蚊子传播的感染引起。他的临床观察进一步推动了癌症免疫治疗领域的发展。他的合作精神和探究精神促进了坎帕拉癌症研究中心的发展。伯基特(Burkitt)在乌干达的遗产影响深远,不仅在乌干达,而且在当今整个血液学-肿瘤学领域都持久存在。