Department of Microbial Physiology,Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborg 7, Groningen, The Netherlands.
Mol Microbiol. 2012 Mar;83(5):884-93. doi: 10.1111/j.1365-2958.2012.07984.x. Epub 2012 Feb 8.
Synthetic Biology is in a critical phase of its development: it has finally reached the point where it can move from proof-of-principle studies to real-world applications. Secondary metabolite biosynthesis, especially the discovery and production of antibiotics, is a particularly relevant target area for such applications of synthetic biology. The first international conference to explore this subject was held in Spain in October 2011. In four sessions on General Synthetic Biology, Filamentous Fungal Systems, Actinomyces Systems, and Tools and Host Structures, scientists presented the most recent technological and scientific advances, and a final-day Forward Look Plenary Discussion identified future trends in the field.
它终于达到了从原理验证研究到实际应用的阶段。次生代谢物生物合成,特别是抗生素的发现和生产,是合成生物学应用的一个特别相关的目标领域。2011 年 10 月,西班牙举行了第一次探讨这个主题的国际会议。在一般合成生物学、丝状真菌系统、放线菌系统以及工具和宿主结构这四个专题会议上,科学家们展示了最新的技术和科学进展,最后一天的前瞻性全体讨论确定了该领域未来的趋势。