La Alamedilla Health Centre, Research unit, Castilla y León Health Service-SACYL, Salamanca, Spain.
Hypertens Res. 2012 Jun;35(6):617-23. doi: 10.1038/hr.2012.3. Epub 2012 Feb 2.
A comparison is made of central aortic systolic pressure (CASP) and the radial augmentation index (rAIx) estimated with the B-Pro device and SphygmoCor (as reference) in 104 healthy Caucasians without drug treatment, together with an analysis of the relationship between CASP and rAIx, and arterial stiffness. Peripheral and central blood pressure, and the rAIx were measured with B-pro and SphygmoCor, with determination of the central augmentation index (CAIx), pulse wave velocity (PWV), carotid intima-media thickness (IMT) and the ankle-brachial index (ABI). rAIx as determined with B-Pro was greater than measured with SphygmoCor (5.85; 95%CI: 1.75-9.96), in the same way as CASP, estimated from the transfer function (1.47; 95%CI: 0.47-2.47 mm Hg) and with the second peak of the radial wave (4.46; 95%CI: 2.80-6.12 mm Hg). The Pearson correlation coefficient for CASP with B-Pro and SphygmoCor was r = 0.937 (P < 0.01), with an intraclass correlation of 0.972 (95%CI: 0.959-0.981). In the case of rAIx, the correlation coefficient was r = 0.436 (P < 0.01), with an intraclass correlation of 0.599 (95% CI: 0.409-0.728). The correlation of CASP (B-pro) with PWV was r = 0.558 (P < 0.01), with CAIx r = 0.253 (P < 0.01) and with carotid IMT r = 0.442 (P < 0.01). The correlation of rAIx (B-Pro) with age was r = 0.369 (r < 0.01), and with CAIx r = 0.463 (P < 0.001). Central arterial pressure estimated with B-Pro in healthy Caucasians without drug treatment offers adequate validity vs. the reference standard (SphygmoCor). However, in the estimation of rAIx, some differences with respect to the reference standard have been detected, probably related to measurement of the second peak of the radial wave.
在 104 名未接受药物治疗的健康白种人受试者中，我们比较了使用 B-Pro 设备和 SphygmoCor（作为参考）估计的中心主动脉收缩压（CASP）和桡动脉增强指数（rAIx），并分析了 CASP 与 rAIx 以及动脉僵硬度之间的关系。外周和中心血压以及 rAIx 使用 B-Pro 和 SphygmoCor 进行测量，并确定中心增强指数（CAIx）、脉搏波速度（PWV）、颈动脉内膜中层厚度（IMT）和踝臂指数（ABI）。使用 B-Pro 确定的 rAIx 大于 SphygmoCor 测量的 rAIx（5.85；95%CI：1.75-9.96），同样，从传递函数（1.47；95%CI：0.47-2.47mmHg）和桡动脉波的第二个峰值（4.46；95%CI：2.80-6.12mmHg）估计的 CASP 也是如此。B-Pro 与 SphygmoCor 测量的 CASP 的 Pearson 相关系数为 r = 0.937（P < 0.01），组内相关系数为 0.972（95%CI：0.959-0.981）。对于 rAIx，相关系数为 r = 0.436（P < 0.01），组内相关系数为 0.599（95%CI：0.409-0.728）。B-pro 测量的 CASP 与 PWV 的相关性 r = 0.558（P < 0.01），与 CAIx 的相关性 r = 0.253（P < 0.01），与颈动脉 IMT 的相关性 r = 0.442（P < 0.01）。B-Pro 测量的 rAIx 与年龄的相关性 r = 0.369（r < 0.01），与 CAIx 的相关性 r = 0.463（P < 0.001）。在未接受药物治疗的健康白种人中，使用 B-Pro 估计的中心动脉压与参考标准（SphygmoCor）具有足够的有效性。然而，在桡动脉增强指数的估计中，与参考标准相比，已经发现了一些差异，这可能与桡动脉波的第二个峰值的测量有关。
