Elgin Ufuk, Sen Emine, Teke Mehmet Y, Tirhis Hakan, Ozturk Faruk
Department of Ophthalmology, Ulucanlar Eye Research Hospital, 24 Sokak, 13/4 06490, Bahcelievler, Ankara, Turkey.
Int Ophthalmol. 2012 Feb;32(1):89-92. doi: 10.1007/s10792-012-9517-5. Epub 2012 Feb 2.
To report a case of microtrauma-induced recurrent hyphema and secondary glaucoma associated with voluntary chronic acetylsalicylic acid (ASA) use. A 43-year-old male developed advanced glaucoma in his right eye after a two-month followup period of recurrent microhyphema, which had been induced by strong eye-rubbing. In spite of topical and systemic antiglaucoma medication, as well as topical corticosteroid and cycloplegic drugs and bed rest under hospitalization, the hyphema and glaucoma were not controlled. His medical history revealed that he had been using ASA for 2 years in order to prevent heart attacks. We asked the patient to stop ASA intake and the hyphema cleared considerably on the third day after discontinuation of the drug. One week after stopping ASA, trabeculectomy with mitomycin C was performed without any complications. Glaucoma and recurrent hyphema were controlled after surgery without any medical treatment. Chronic ASA intake may cause recurrent hyphema and secondary glaucoma even after a microtrauma. Medical histories of patients must always be taken, especially in cases of prolonged recurrent hyphema.
报告一例因微小创伤诱发的反复前房积血及继发性青光眼病例，该病例与长期自愿服用乙酰水杨酸（ASA）有关。一名43岁男性在经历了两个月因用力揉眼诱发的反复微小前房积血的随访期后，右眼发展为晚期青光眼。尽管使用了局部及全身抗青光眼药物，以及局部皮质类固醇、睫状肌麻痹药物并住院卧床休息，前房积血和青光眼仍未得到控制。其病史显示，他为预防心脏病发作已服用ASA两年。我们要求患者停止服用ASA，停药后第三天前房积血明显消退。停用ASA一周后，进行了丝裂霉素C辅助的小梁切除术，未出现任何并发症。术后无需任何药物治疗，青光眼和反复前房积血即得到控制。长期服用ASA即使在微小创伤后也可能导致反复前房积血和继发性青光眼。必须始终询问患者的病史，尤其是在长期反复前房积血的病例中。
