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眼部整形手术中的阿司匹林和华法林治疗

Aspirin and warfarin therapy in oculoplastic surgery.

作者信息

Parkin B, Manners R

机构信息

Southampton Eye Unit, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK.

出版信息

Br J Ophthalmol. 2000 Dec;84(12):1426-7. doi: 10.1136/bjo.84.12.1426.

Abstract

BACKGROUND/AIMS: There are no nationally agreed guidelines on preoperative management of patients who are on aspirin or warfarin therapy. There is considerable evidence that complication rates in anticoagulated patients are low whereas there are higher rates of thromboembolic complications in those whose therapy is manipulated. This survey aimed to establish oculoplastic specialist and non-specialist ophthalmic surgeons' current management practice of patients before oculoplastic surgery who are taking aspirin or warfarin and to assess the rate of complications in these patients.

METHOD

An anonymous postal questionnaire survey of all ophthalmic consultants and specialist registrars in the Wessex region along with oculoplastic specialists in the Southern region.

RESULTS

The overall response rate was 92%. Preoperative management was influenced both by type of operation and by type of surgeon. A statistically significant higher proportion of surgeons would consider altering warfarin compared with aspirin treatment. For all procedures, non-specialists are unlikely to stop aspirin therapy, and are less likely to stop warfarin before all procedures apart from dacrocystorhinostomy. A significant proportion of surgeons (18%) would allow insufficient time for the coagulation status of the patient to change after altering treatment. A considerable proportion of surgeons (54%) reported that they had seen complications as a result either of stopping or continuing anticoagulation therapy.

CONCLUSIONS

In this survey, at least half the surgeons questioned would consider stopping warfarin before oculoplastic procedures. Over half of all surgeons have seen complications related to aspirin or warfarin, some of which were serious. A suggested approach to minimising patient risk is given.

摘要

背景/目的:对于正在接受阿司匹林或华法林治疗的患者,目前尚无全国统一认可的术前管理指南。有大量证据表明,接受抗凝治疗的患者并发症发生率较低,而那些治疗被调整的患者血栓栓塞并发症发生率较高。本次调查旨在确定眼整形专科医生和非专科眼科医生目前对接受阿司匹林或华法林治疗的患者在眼整形手术前的管理做法,并评估这些患者的并发症发生率。

方法

对韦塞克斯地区的所有眼科顾问和专科住院医生以及南部地区的眼整形专科医生进行了一次匿名邮寄问卷调查。

结果

总体回复率为92%。术前管理受手术类型和外科医生类型的影响。与阿司匹林治疗相比,考虑改变华法林治疗的外科医生比例在统计学上显著更高。对于所有手术,非专科医生不太可能停止阿司匹林治疗,除泪囊鼻腔吻合术外,在所有手术前停止华法林治疗的可能性也较小。相当一部分外科医生(18%)在改变治疗后给患者凝血状态改变的时间不足。相当一部分外科医生(54%)报告称,他们见过因停止或继续抗凝治疗而导致的并发症。

结论

在本次调查中,至少一半接受询问的外科医生会考虑在眼整形手术前停止华法林治疗。超过一半的外科医生见过与阿司匹林或华法林相关的并发症,其中一些很严重。文中给出了一种将患者风险降至最低的建议方法。

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