Heeren T J, Lagaay A M, von Beek W C, Rooymans H G, Hijmans W
Department of Psychiatry, Leiden University, The Netherlands.
J Am Geriatr Soc. 1990 Oct;38(10):1093-6. doi: 10.1111/j.1532-5415.1990.tb01371.x.
The Mini-Mental State Examination (MMSE) was used in a population survey of all inhabitants of Leiden, the Netherlands, over 85 years (n = 1258). In this paper we report on 532 subjects without neurological or psychiatric disease. Results show that the median score and lowest quartile cut-off score remain high until the tenth decade (median score = 28, lowest quartile cut-off score = 26). Thus age, in itself, is not a major limitation in using the MMSE. In this study a comparatively low level of education (the majority had 6 to 7 years of education) did not affect the results on the MMSE in a negative way, nor did we find an association with the use of psychoactive drugs.
简易精神状态检查表（MMSE）用于对荷兰莱顿所有85岁以上居民（n = 1258）进行的人口调查。在本文中，我们报告了532名无神经或精神疾病的受试者。结果显示，直到第十个十年，中位数得分和最低四分位数截止分数仍保持较高水平（中位数得分 = 28，最低四分位数截止分数 = 26）。因此，年龄本身并非使用MMSE的主要限制因素。在本研究中，相对较低的教育水平（大多数人接受过6至7年教育）并未对MMSE结果产生负面影响，我们也未发现其与使用精神活性药物之间存在关联。
