Department of Obstetrics and Gynecology, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of Negev, Be'er-Sheva, Israel.
Surg Obes Relat Dis. 2012 Jul-Aug;8(4):434-9. doi: 10.1016/j.soard.2011.12.009. Epub 2011 Dec 24.
Overweight and obesity have been shown to be associated with increased adverse pregnancy outcomes. Weight reduction improves maternal health status and reduces the risk of pregnancy complications, as well as long-term consequences. Our objective was to compare the pregnancy outcomes of the same women who delivered before and after bariatric surgery.
A retrospective study comparing pregnancy outcomes, of the same women, delivered before and after a bariatric surgery was conducted. The observed deliveries occurred from 1988 to 2008 at Soroka University Medical Center, the sole tertiary hospital in the southern region of Israel.
The present study included 288 paired pregnancies: 144 deliveries before and 144 after bariatric surgery. A significant reduction in the prepregnancy and predelivery maternal body mass index was noted after bariatric surgery (36.37 ± 5.2 versus 30.50 ± 5.4 kg/m(2), P < .001; and 40.15 ± 4.92 versus 34.41 ± 5.42 kg/m(2), P < .001; respectively). Only 8 patients (5.6%) were admitted during their pregnancy for bariatric complications. Pregnancy complications, such as hypertensive disorders (31.9% versus 16.6%; P = .004) and diabetes mellitus (20.8% versus 7.6%; P = .001), were significantly reduced after bariatric surgery. The rate of cesarean deliveries because of labor dystocia was significantly lower after bariatric surgery (5.6% versus 2.1%, P < .05). Using a multiple logistic regression model, controlling for maternal age, the reduction in hypertensive disorders (odds ratio .4, 95% confidence interval .2-.8) and diabetes mellitus (odds ratio .15, 95% confidence interval .1-.4) remained significant.
A significant decrease in pregnancy complications, such as hypertensive disorders and diabetes mellitus, is achieved after bariatric surgery.
超重和肥胖与不良妊娠结局的风险增加有关。减轻体重可以改善产妇的健康状况,降低妊娠并发症的风险以及长期后果。我们的目的是比较同一组女性在接受减肥手术前后的妊娠结局。
对在以色列南部唯一的三级医院索罗卡大学医学中心分娩的同一组女性进行了减肥手术前后妊娠结局的回顾性研究。
本研究共纳入 288 对妊娠:144 例分娩前和 144 例分娩后进行减肥手术。减肥手术后,产妇孕前和产前的体重指数显著下降(36.37 ± 5.2 对 30.50 ± 5.4 kg/m²,P <.001;40.15 ± 4.92 对 34.41 ± 5.42 kg/m²,P <.001)。仅 8 例(5.6%)患者在妊娠期间因减肥并发症而住院。减肥手术后,妊娠并发症(如高血压疾病(31.9%对 16.6%;P =.004)和糖尿病(20.8%对 7.6%;P =.001))显著减少。由于分娩困难而行剖宫产的比例也显著降低(5.6%对 2.1%,P <.05)。使用多因素逻辑回归模型,控制产妇年龄后,高血压疾病(比值比.4,95%置信区间.2-.8)和糖尿病(比值比.15,95%置信区间.1-.4)的风险仍显著降低。
减肥手术后,高血压疾病和糖尿病等妊娠并发症的发生率显著降低。