使用 LeGoo 热可逆聚合物进行外周血管旁路无夹闭远端吻合的初步结果。

First results of clampless distal anastomosis in peripheral vascular bypass with LeGoo, a thermoreversible polymer.

机构信息

Service de chirurgie cardio vasculaire CHU Le Bocage, Dijon, France.

出版信息

J Vasc Surg. 2012 Jun;55(6):1821-5. doi: 10.1016/j.jvs.2011.11.103. Epub 2012 Feb 1.

DOI:10.1016/j.jvs.2011.11.103

PMID:22301211

Abstract

BACKGROUND

We report our initial experience with LeGoo (Pluromed Inc, Woburn, Mass), a temporary thermoreversible occlusive gel, in peripheral vascular revascularization.

METHODS

Between 2007 and 2010, LeGoo was used to occlude target vessels during bypass surgery in 14 patients who required infrainguinal revascularization.

RESULTS

Proximal occlusion of the target vessel was obtained with a mean quantity of 0.25 mL of LeGoo. Distal occlusion of the vessel was obtained with a mean quantity of 0.28 mL. One injection of LeGoo was sufficient to prevent backbleeding in 11 of 14 patients. The mean occlusion time was 13.4 ± 3.3 minutes. An injection of saline through the graft or better directly into the arteries was used to dissolve the gel. For our first case, a Fogarty catheter was used to remove residual gel from the anterior tibial artery.

CONCLUSIONS

LeGoo gel can be used to stop blood flow in small-bore arteries in the lower limbs to allow anastomoses to be performed.

摘要

背景

我们报告了 LeGoo（Pluromed Inc，马萨诸塞州沃本市）在周围血管血运重建中的初步应用经验，LeGoo 是一种临时热可逆闭塞凝胶。

方法

在 2007 年至 2010 年间，14 名需要下肢血运重建的患者在旁路手术中使用 LeGoo 闭塞目标血管。

结果

用 LeGoo 平均 0.25 mL 获得目标血管的近端闭塞，平均 0.28 mL 获得血管的远端闭塞。14 名患者中有 11 名患者，1 次注射 LeGoo 即可防止逆行出血。平均闭塞时间为 13.4 ± 3.3 分钟。通过移植物或更好地直接向动脉内注射盐水来溶解凝胶。对于我们的首例病例，使用 Fogarty 导管从胫前动脉清除残留的凝胶。