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对实验感染三趾硬皮线虫的仓鼠进行的组织病理学和组织化学研究。

Histopathological and histochemical studies on experimentally infected hamsters with Stictodora tridactyla.

作者信息

Abou-Zakham A A, Atwan N I, Sirag S M

机构信息

Department of Parasitology, Faculty of Medicine, Mansoura University.

出版信息

J Egypt Soc Parasitol. 1990 Dec;20(2):653-8.

PMID:2230322
Abstract

Histopathological changes in the intestinal mucosa in the form of inflammation with atrophic changes in the villi and foci of cellular reaction were seen at the sites of experimental infection in hamsters with Stictodora tridactyla. The activity of succinic dehydrogenase, non specific esterase and alkaline phosphatase enzymes in the villi and the activity of acid phosphatase in the glands were markedly reduced. These changes suggest a disturbance in both digestive and absorptive mechanisms of the small intestine.

摘要

在感染三趾硬皮线虫的仓鼠实验感染部位,可见肠道黏膜出现组织病理学变化,表现为绒毛萎缩性改变及细胞反应灶的炎症。绒毛中琥珀酸脱氢酶、非特异性酯酶和碱性磷酸酶的活性以及腺体中酸性磷酸酶的活性均显著降低。这些变化提示小肠的消化和吸收机制均受到干扰。

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