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双组分信号元件与组氨酰-天冬氨酰磷酸化信号转导

Two-component signaling elements and histidyl-aspartyl phosphorelays.

作者信息

Schaller G Eric, Kieber Joseph J, Shiu Shin-Han

出版信息

Arabidopsis Book. 2008;6:e0112. doi: 10.1199/tab.0112. Epub 2008 Jul 14.

Abstract

Two-component systems are an evolutionarily ancient means for signal transduction. These systems are comprised of a number of distinct elements, namely histidine kinases, response regulators, and in the case of multi-step phosphorelays, histidine-containing phosphotransfer proteins (HPts). Arabidopsis makes use of a two-component signaling system to mediate the response to the plant hormone cytokinin. Two-component signaling elements have also been implicated in plant responses to ethylene, abiotic stresses, and red light, and in regulating various aspects of plant growth and development. Here we present an overview of the two-component signaling elements found in Arabidopsis, including functional and phylogenetic information on both bona-fide and divergent elements.

摘要

双组分系统是一种进化上古老的信号转导方式。这些系统由许多不同的元件组成,即组氨酸激酶、响应调节因子,以及在多步磷酸化中继的情况下,含组氨酸的磷酸转移蛋白(HPts)。拟南芥利用双组分信号系统来介导对植物激素细胞分裂素的响应。双组分信号元件也参与了植物对乙烯、非生物胁迫和红光的响应,以及调节植物生长和发育的各个方面。在这里,我们概述了拟南芥中发现的双组分信号元件,包括真正元件和不同元件的功能及系统发育信息。

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