Soffar S A
Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
J Egypt Soc Parasitol. 1990 Dec;20(2):841-7.
Absolute eosinophilic counts to different developmental stages of Trichinella spiralis in experimental trichinosis were studied to identify the stage responsible for eosinophilia. Two peaks of eosinophilia were noticed, the first (545 +/- 172.3) was attributed to the adult stage while the migrating larvae were accused to be responsible for the more pronounced second peak (1265 +/- 331.7). With encapsulation a steady raised level was demonstrated. Chromatographic studies to determine the nature of eosinophilogens produced by the different stages are recommended. The role of eosinophils in damaging the parasite is discussed in details. No correlation could be determined between muscle larval burden and eosinophilic count.
研究了实验性旋毛虫病中旋毛虫不同发育阶段的绝对嗜酸性粒细胞计数，以确定导致嗜酸性粒细胞增多的阶段。观察到两个嗜酸性粒细胞增多的峰值，第一个峰值（545±172.3）归因于成虫阶段，而移行幼虫被认为是导致更明显的第二个峰值（1265±331.7）的原因。随着包囊形成，呈现出稳定升高的水平。建议进行色谱研究以确定不同阶段产生的嗜酸性粒细胞生成素的性质。详细讨论了嗜酸性粒细胞在破坏寄生虫中的作用。未发现肌肉幼虫负荷与嗜酸性粒细胞计数之间存在相关性。
