Pattern of eosinophilia and muscle larval burdens in experimental trichinosis.

Absolute eosinophilic counts to different developmental stages of Trichinella spiralis in experimental trichinosis were studied to identify the stage responsible for eosinophilia. Two peaks of eosinophilia were noticed, the first (545 +/- 172.3) was attributed to the adult stage while the migrating larvae were accused to be responsible for the more pronounced second peak (1265 +/- 331.7). With encapsulation a steady raised level was demonstrated. Chromatographic studies to determine the nature of eosinophilogens produced by the different stages are recommended. The role of eosinophils in damaging the parasite is discussed in details. No correlation could be determined between muscle larval burden and eosinophilic count.