Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, 600 North Wolfe Street, 565C Carnegie Building, Baltimore, MD 21287, USA.
Cardiol Clin. 2012 Feb;30(1):135-46. doi: 10.1016/j.ccl.2011.11.007. Epub 2011 Dec 12.
Coronary computed tomography angiography (CTA) is a reliable diagnostic test for the anatomic diagnosis of obstructive coronary artery disease (CAD). Although coronary CTA shows high sensitivity and negative predictive value for detecting stenosis greater than or equal to 50% diameter, it is limited in its ability to diagnose myocardial ischemia. Advances in computed tomography (CT) technology alone and technology that hybridizes CT with single-photon emission CT and positron emission tomography allow for the combined anatomic and physiologic diagnosis of CAD. This article summarizes these combined technologies, emphasizing the merits and limitations of each technology and their clinical implications.
冠状动脉计算机断层扫描血管造影（CTA）是一种可靠的诊断方法，可用于解剖学诊断阻塞性冠状动脉疾病（CAD）。虽然冠状动脉 CTA 在检测大于或等于 50%直径狭窄方面具有较高的敏感性和阴性预测值，但在诊断心肌缺血方面存在局限性。计算机断层扫描（CT）技术的进步以及将 CT 与单光子发射 CT 和正电子发射断层扫描相结合的技术，使得 CAD 的解剖学和生理学联合诊断成为可能。本文总结了这些联合技术，强调了每种技术的优点和局限性及其临床意义。
