Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.
J Chromatogr A. 2012 Mar 16;1229:1-5. doi: 10.1016/j.chroma.2011.12.110. Epub 2012 Jan 10.
Hollow fiber protected liquid phase microextraction using an ionic liquid as supported phase and acceptor phase (IL-HF-LPME) is proposed for the determination of four ultraviolet (UV) filters (benzophenone, 3-(4-methylbenzylidene)-camphor, 2-hydroxy-4-methoxybenzophenone and 2,4-dihydroxybenzophenone) in water samples for the first time. In the present study, four different ILs 1-hexyl-3-methylimidazolium tris(pentafluoroethyl)trifluorophosphate) [HMIM][FAP], 1-butyl-1-methylpyrrolidinium tris(pentafluoroethyl)trifluorophosphate [BMPL][FAP], 1-butyl-3-methylimidazolium phosphate ([BMIM][PO(4)]) and 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF(6)]) were evaluated as extraction solvent. Only [HMIM][FAP] showed high chemical affinity to the analytes which permits a selective isolation of the UV filters from the sample matrix, allowing also their preconcentration. IL-HF-LPME and high performance liquid chromatography provides repeatability from 1.1% to 8.2% and limits of detection between 0.3 and 0.5 ng/ml. Real water samples spiked with the analytes extracted were analyzed, and yielded relative recoveries ranging from 82.6% to 105.9%.
首次提出了一种使用离子液体作为支撑相和接受相的中空纤维保护液相微萃取（IL-HF-LPME）方法，用于测定水样中的四种紫外（UV）过滤器（二苯甲酮、3-（4-甲基亚苄基）-樟脑、2-羟基-4-甲氧基二苯甲酮和 2,4-二羟基二苯甲酮）。在本研究中，评估了四种不同的离子液体 1-己基-3-甲基咪唑六氟磷酸盐[HMIM][FAP]、1-丁基-1-甲基吡咯烷六氟磷酸盐[BMPL][FAP]、1-丁基-3-甲基咪唑磷酸盐([BMIM][PO(4)])和 1-丁基-3-甲基咪唑六氟磷酸盐([BMIM][PF(6)])作为萃取溶剂。只有[HMIM][FAP]对分析物表现出高化学亲和力，允许从样品基质中选择性分离 UV 过滤器，并允许对其进行预浓缩。IL-HF-LPME 和高效液相色谱法提供了从 1.1%到 8.2%的重复性和 0.3 到 0.5ng/ml 的检测限。对用分析物提取的实际水样进行了分析，相对回收率在 82.6%到 105.9%之间。
