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A synthetic peptide elicits antibody reactive with the native duck hepatitis B virus pre-S protein.

作者信息

Wen Y M, Xu Y Y, Zhang W, Liu Y Z

机构信息

Department of Microbiology, Shanghai Medical University, People's Republic of China.

出版信息

J Gen Virol. 1990 Oct;71 ( Pt 10):2467-9. doi: 10.1099/0022-1317-71-10-2467.

DOI:10.1099/0022-1317-71-10-2467
PMID:2230741
Abstract

Synthetic peptides P37-49 and P63-79, derived from the pre-S region of duck hepatitis B virus (DHBV), have been synthesized. Only P37-49 was reactive with rabbit anti-DHBs/pre-S antibodies by radioimmunoprecipitation. Antiserum prepared against P37-47 reacted with a 35K polypeptide of native DHBs/pre-S by immunoblotting. It is concluded that P37-49 (MGQHPAKSMDVRR) mimics one of the epitopes of the DHBV pre-S antigen.

摘要

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