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Wernekink 连合综合征:一种罕见的中脑综合征。

Wernekink commissure syndrome: a rare midbrain syndrome.

机构信息

Department of Neurology, First Affiliated Hospital, China Medical University, No.155, North Nanjing Street, 110001, Shenyang, China.

出版信息

Neurol Sci. 2012 Dec;33(6):1419-21. doi: 10.1007/s10072-012-0966-4. Epub 2012 Feb 4.

DOI:10.1007/s10072-012-0966-4
PMID:22307446
Abstract

Wernekink commissure syndrome is a rare midbrain syndrome, which selectively destroys the Wernekink commissure involving the decussation of superior cerebellar peduncle in midbrain. This syndrome may display a clinical picture: bilateral cerebellar ataxia, eye movement disorders, and palatal tremor. We present two cases of the Wernekink commissure syndrome with acute onset of bilateral cerebellar dysfunction confirmed by magnetic resonance imaging. One patient presented internuclear ophthalmoplegia, but neither showed palatal tremor. It is notable that the bilateral cerebellar dysfunction may be ascribed to midbrain lesion involving the Wernekink commissure, and it may be the sole manifestation of the midbrain lesion.

摘要

韦内肯 commissure 综合征是一种罕见的中脑综合征,选择性地破坏韦内肯 commissure,涉及中脑内上小脑脚的交叉。该综合征可能表现为以下临床特征:双侧小脑共济失调、眼球运动障碍和腭震颤。我们报告了两例韦内肯 commissure 综合征,均为双侧小脑功能障碍急性发作,磁共振成像证实。其中 1 例患者表现为核间性眼肌麻痹,但均无腭震颤。值得注意的是,双侧小脑功能障碍可能归因于中脑病变累及韦内肯 commissure,也可能是中脑病变的唯一表现。

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本文引用的文献

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A caudal mesencephalic infarct presenting only with tetra-ataxia and tremor.仅表现为四叠体共济失调和震颤的中脑尾端梗死
Cerebrovasc Dis. 2008;25(1-2):187-9. doi: 10.1159/000113737. Epub 2008 Jan 25.
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Wernekink comissure syndrome: a rare midbrain syndrome secondary to stroke.韦尼克连合综合征:一种罕见的中风继发中脑综合征。
J Pak Med Assoc. 2006 Jun;56(6):289-90.
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Caudal paramedian midbrain syndrome.尾侧旁正中脑综合征
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Wernekinck Commissure Syndrome: Sequela of a Caudal Paramedian Midbrain Infarction.韦内金克连合综合征:中脑尾侧旁正中梗死的后遗症
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Wernekink commissure syndrome with palatal myoclonus at onset: a case report and review of the literature.韦尼克连合综合征起病时伴有腭肌阵挛:一例病例报告及文献复习
J Med Case Rep. 2018 May 1;12(1):113. doi: 10.1186/s13256-018-1657-4.
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The "heart appearance" sign on MRI of Wernekink's commissure syndrome caused by bilateral caudal paramedian midbrain infarction.由双侧尾侧中脑旁正中梗死引起的韦尼克连合综合征MRI上的“心脏外观”征。
Neurol Sci. 2018 Mar;39(3):587-589. doi: 10.1007/s10072-017-3159-3. Epub 2017 Oct 23.
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Wernekink Commissure Syndrome Secondary to Bilateral Caudal Paramedian Midbrain Infarction Presenting with a Unique "Heart or V" Appearance Sign: Case Report and Review of the Literature.双侧中脑尾侧旁正中梗死继发韦尼克交叉综合征伴独特“心脏或V”形外观征:病例报告及文献复习
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Bilateral Hypertrophic Olivary Degeneration and Holmes Tremor without Palatal Tremor: An Unusual Association.双侧肥厚性橄榄体变性与无腭震颤的霍姆斯震颤:一种不寻常的关联。
Tremor Other Hyperkinet Mov (N Y). 2016 Jul 14;6:400. doi: 10.7916/D87944SS. eCollection 2016.
Neurology. 2006 Jun 13;66(11):1668-71. doi: 10.1212/01.wnl.0000218180.03127.11.
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