Centre Hospitalier Régional et Universitaire de Tours, Service Oto-Rhino-Laryngologie et Chirurgie Cervico Faciale, Tours, France.
Head Neck. 2013 May;35(5):E164-6. doi: 10.1002/hed.22905. Epub 2012 Feb 6.
Lipoleiomyosarcoma is a rare tumor consisting of well-differentiated liposarcoma and leiomyosarcoma. The ear-nose-throat location of lipoleiomyosarcoma has not been previously described.
A 37-year-old man with a dysphagia had a dyspnea after an endoscopy. A large tumor was exteriorized from the man's mouth. The lesion was pedicled to the epiglottis. A histologic examination determined that the tumor was a lipoleiomyosarcoma. MDM2 and CDK4 gene amplification were positive. Due to the risk of recurrence, a second intervention was performed to complete the excision.
These tumors develop in cavities slowly and gradually. The treatment of this lesion is surgical with a sufficient resection margin.
脂肪肉瘤样平滑肌肉瘤是一种罕见的肿瘤，由分化良好的脂肪肉瘤和平滑肌肉瘤组成。耳部、鼻部和喉部的脂肪肉瘤样平滑肌肉瘤以前尚未有过描述。
一名 37 岁男子因吞咽困难在接受内镜检查后出现呼吸困难。一个大肿瘤从男子口中突出。病变有蒂与会厌相连。组织学检查确定肿瘤为脂肪肉瘤样平滑肌肉瘤。MDM2 和 CDK4 基因扩增阳性。由于存在复发风险，进行了第二次干预以完成切除。
这些肿瘤在腔隙中缓慢逐渐生长。该病变的治疗方法是手术切除，切除范围要足够。
