Department of Internal Medicine, Division of Pulmonary & Critical Care Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.
J Natl Compr Canc Netw. 2012 Feb;10(2):277-85. doi: 10.6004/jnccn.2012.0024.
This article summarizes what is known about the best practices of lung cancer screening and provides suggestions for the proper structure for institutions considering offering lung cancer screening services. Important points of emphasis include the need to confine screening to patients at highest risk, the presence of multidisciplinary teams capable of managing the high number of false-positive findings, the need for additional research on biomarkers and risk models for lung cancer, and the currently unknown cost-effectiveness of lung cancer screening on a societal level.
本文总结了肺癌筛查的最佳实践,并为考虑提供肺癌筛查服务的机构提供了适当的结构建议。重点包括需要将筛查仅限于高危患者、存在能够管理大量假阳性结果的多学科团队、需要对肺癌生物标志物和风险模型进行更多研究、以及目前尚不清楚在社会层面上肺癌筛查的成本效益。