Koutlaki N, Dimitraki M, Zervoudis S, Sofiadou V, Grapsas X, Psillaki A, Nikas I, Galazios G, Liberis V, Voiculescu S, Burcoş T
Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece.
Chirurgia (Bucur). 2011 Nov-Dec;106(6):715-22.
Borderline ovarian tumors account for 15-20% of all ovarian epithelial tumors. Since their original description in 1929, our knowledge of their natural history and molecular pathology has advanced most dramatically over the last two decades. This improved knowledge of BOT has permitted to drastically decrease the therapeutics of these tumors, which remains mostly surgical.
We studied the available literature on surgical management of BOT accentuating the most important aspects on this topic: radical vs. conservative treatment, fertility preservation.
Although there are conflicting reports about some of the aspects of surgical management of these tumors, since BOTs commonly affect women of reproductive age, who have not completed childbearing, have an excellent overall prognosis and the majority of them (approximately 50% to 85%) are stage I at diagnosis, conservative surgery (unilateral salpingo-oophorectomy or cystectomy) can be safely performed after comprehensive surgical staging, in order to preserve fertility.
Conservative surgery could be safely performed in young patients treated for BOT, provided that they are carefully followed-up.
交界性卵巢肿瘤占所有卵巢上皮性肿瘤的15% - 20%。自1929年首次描述以来，在过去二十年中，我们对其自然史和分子病理学的认识有了最为显著的进展。对交界性卵巢肿瘤的这种深入了解使得这些肿瘤的治疗方法大幅减少，目前其治疗仍主要以手术为主。
我们研究了有关交界性卵巢肿瘤手术治疗的现有文献，着重探讨了该主题的最重要方面：根治性治疗与保守性治疗、生育功能保留。
尽管关于这些肿瘤手术治疗的某些方面存在相互矛盾的报道，但由于交界性卵巢肿瘤通常影响育龄期、尚未完成生育的女性，其总体预后良好，且大多数患者（约50%至85%）在诊断时处于I期，因此在进行全面的手术分期后，可以安全地实施保守性手术（单侧输卵管卵巢切除术或囊肿切除术）以保留生育功能。
对于接受交界性卵巢肿瘤治疗的年轻患者，只要进行仔细的随访，就可以安全地实施保守性手术。
