Wang Dan, Zhang Guo-Bin, Yan Lei, Wei Xiao-Er, Zhang Yu-Zhen, Li Wen-Bin
Shanghai Jiao Tong University Medical Imaging Institute, Institute of Diagnostic and Interventional Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, No. 600, Yi Shan Road, Shanghai, 200233, China.
Abdom Imaging. 2012 Oct;37(5):738-45. doi: 10.1007/s00261-011-9836-4.
To enhance diagnosis of gastrointestinal neuroendocrine carcinomas using CT and contrast-enhanced CT images.
A total of 44 patients with gastrointestinal neuroendocrine carcinomas, as confirmed by clinical pathology and immunohistochemistry in the Sixth Affiliated People's Hospital of Shanghai Jiao Tong University Shanghai China, were included in the study. CT and enhanced CT scanning were performed, and the resulting images were reviewed and analyzed.
Twenty-seven males and 17 females were enrolled. Gastrointestinal involvement included the following: 5 cases located in the middle or inferior segment of the esophagus; 5 in the gastric cardia, 15 in the body of stomach, 6 located in the gastric antrum; 5 located in the Vater papilla of the duodenum; and 8 located in the colon. Among the 44 cases 80%-90% of the lesions had homogeneous density. Totally 81.8% (36/44) cases demonstrated homogeneous enhancement in arterial phases, most of the cases (n = 33) moderately or obviously enhanced. Only 17.2% (8/44) cases appeared as heterogeneous enhancement. And 86.4% cases (n = 38) were further enhanced in the venous phase. The CT images also revealed some of the metastases. Some liver metastasis cases have obvious homogeneous enhancement.
CT and enhanced CT provide useful information regarding gastrointestinal neuroendocrine carcinomas' location, density, enhancement pattern, and some metastasis. These features are helpful to increase the diagnostic accuracy.
利用CT及增强CT图像提高胃肠道神经内分泌癌的诊断水平。
纳入上海交通大学附属第六人民医院经临床病理及免疫组化确诊的44例胃肠道神经内分泌癌患者。行CT及增强CT扫描，对所得图像进行回顾性分析。
纳入27例男性和17例女性。胃肠道受累情况如下：5例位于食管中下段；5例位于贲门，15例位于胃体，6例位于胃窦；5例位于十二指肠乳头；8例位于结肠。44例中80% - 90%的病灶密度均匀。81.8%（36/44）的病例在动脉期呈均匀强化，大多数病例（n = 33）呈中度或明显强化。仅17.2%（8/44）的病例表现为不均匀强化。86.4%的病例（n = 38）在静脉期进一步强化。CT图像还显示了部分转移情况。部分肝转移病例有明显的均匀强化。
CT及增强CT能提供有关胃肠道神经内分泌癌的位置、密度、强化方式及部分转移情况的有用信息。这些特征有助于提高诊断准确性。
