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脊柱疾病退伍军人的健康相关生活质量状况。

Health-related quality-of-life status in Veterans with spinal disorders.

机构信息

Outcomes Research Lab, VA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304, USA.

出版信息

Qual Life Res. 2013 Feb;22(1):45-52. doi: 10.1007/s11136-012-0121-y. Epub 2012 Feb 5.

Abstract

PURPOSE

To measure the impact of spinal disorders on health-related quality of life (HRQOL) among Veterans, to describe demographic patterns of Veterans with spinal disorders, and to quantify HRQOL scores as they relate to demographics, medical comorbidities, pain severity, and depressive symptoms.

METHODS

From 2009 to 2010, 112 lumbar and 56 cervical spinal disorder patients completed SF-12, Oswestry Disability Index, visual analog pain scale, and Beck Depression Inventory surveys. Multivariate analysis identified predictors of HRQOL, disability, and depressive symptoms.

RESULTS

A total of 168 patients completed surveys for this study. The median age of all patients was 60. Nearly 30% of lumbar and 16% of cervical patients were aged 65 or older. Approximately 96% of patients were men. Sixty percent of patients were currently receiving or had pending disability compensation. Nearly 60% of patients were current smokers, approximately 26% reported alcoholism or intravenous drug use, and 26% self-reported post-traumatic stress disorder. The most common lumbar spine diagnoses were disk herniation (36.6%) and stenosis (34.8%), and most common cervical spine diagnoses were stenosis (50.0%) and disk herniation (23.2%). Back pain was reported by 93.8% of lumbar patients and leg pain by 83.0%. Neck pain was reported by 96.4% of cervical patients and arm pain by 69.6%. Median SF-12 physical component scores were more than two standard deviations below the US average. Ninety percent of patients had at least moderate physical disability. Sixty-four percent met criteria for depressive symptoms. Visual analog pain score was the strongest predictor of SF-12 physical (β = -1.32, P < 0.001) and mental (β = -1.63, P < 0.001) HRQOL and was the prime determinant of depressive symptoms (β = 1.52, P < 0.001) and disability index score (β = 4.39, P < 0.0001). Charlson Comorbidity Score and smoking status had no significant impact on HRQOL or disability scores. Age was negatively correlated with depressive symptoms and positively correlated with SF-12 mental component scores.

CONCLUSIONS

Spinal disorders have a severe impact on both physical and emotional HRQOL of Veterans and are associated with severe disability and an unusually high prevalence of depressive symptoms. Therapeutic interventions should be targeted to reduce pain, which is a prime determinant of HRQOL, disability, and depressive symptoms. Given high prevalence of multiple risk factors for poor outcomes, studies of spine surgery outcomes in Veterans are needed.

摘要

目的

测量脊柱疾病对退伍军人健康相关生活质量(HRQOL)的影响,描述患有脊柱疾病的退伍军人的人口统计学模式,并量化 HRQOL 评分与人口统计学、医学合并症、疼痛严重程度和抑郁症状的关系。

方法

2009 年至 2010 年,112 例腰椎和 56 例颈椎脊柱疾病患者完成了 SF-12、Oswestry 残疾指数、视觉模拟疼痛量表和贝克抑郁量表调查。多变量分析确定了 HRQOL、残疾和抑郁症状的预测因素。

结果

共有 168 名患者完成了这项研究的调查。所有患者的中位年龄为 60 岁。近 30%的腰椎和 16%的颈椎患者年龄在 65 岁或以上。大约 96%的患者是男性。60%的患者正在接受或正在申请残疾赔偿。近 60%的患者是当前吸烟者,约 26%报告酗酒或静脉内药物使用,26%自我报告创伤后应激障碍。最常见的腰椎脊柱诊断是椎间盘突出症(36.6%)和狭窄症(34.8%),最常见的颈椎脊柱诊断是狭窄症(50.0%)和椎间盘突出症(23.2%)。93.8%的腰椎患者报告背痛,83.0%的患者报告腿痛。96.4%的颈椎患者报告颈部疼痛,69.6%的患者报告手臂疼痛。SF-12 生理成分评分中位数比美国平均值低两个标准差以上。90%的患者有中度以上的身体残疾。64%的患者符合抑郁症状标准。视觉模拟疼痛评分是 SF-12 生理(β=-1.32,P<0.001)和心理(β=-1.63,P<0.001)HRQOL 的最强预测因子,也是抑郁症状(β=1.52,P<0.001)和残疾指数评分(β=4.39,P<0.0001)的主要决定因素。Charlson 合并症评分和吸烟状况对 HRQOL 或残疾评分没有显著影响。年龄与抑郁症状呈负相关,与 SF-12 心理成分评分呈正相关。

结论

脊柱疾病对退伍军人的生理和心理 HRQOL 都有严重影响,并与严重残疾和异常高的抑郁症状发生率相关。治疗干预措施应针对减轻疼痛,疼痛是 HRQOL、残疾和抑郁症状的主要决定因素。鉴于不良结局的多种危险因素的高发生率,需要对退伍军人的脊柱手术结果进行研究。

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