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成年男性体重指数、精液与性激素之间的关系

The relationship between body mass index, semen and sex hormones in adult male.

作者信息

Egwurugwu J N, Nwafor A, Chike C P R, Ufearo C S, Uchefuna R C, Iwuji S C, Okwara J E, Alagwu E A

机构信息

Department of physiology, Imo state University, Owerri, Nigeria.

出版信息

Niger J Physiol Sci. 2011 Nov 23;26(1):29-34.

Abstract

This study was aimed at evaluating the relationship between body mass index, sex hormones and semen characteristics in male adults. 120 male adults aged 20 to 50 years who consented to participate in the study were used. Serum samples collected from each subject were analyzed for luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin (PRL), progesterone, estradiol and testosterone by classical ELISA method. Semen samples obtained by masturbation after 72 hours of abstinence were analyzed for sperm count and motility. The results showed statistically significant correlations at 99% confidence level between body mass index and serum concentrations of progesterone and oestradiol and sperm count. No significant correlations were observed between body mass index and sperm motility, serum concentrations of prolactin, testosterone and luteinizing hormone. In conclusion, this study has shown that statistically significant correlations exist between body mass index, semen characteristics and male sex hormones and may broaden our understanding of the physiology of male fertility/infertility.

摘要

本研究旨在评估成年男性体重指数、性激素与精液特征之间的关系。选取了120名年龄在20至50岁之间且同意参与研究的成年男性。采用经典酶联免疫吸附测定(ELISA)法对从每个受试者采集的血清样本进行促黄体生成素(LH)、促卵泡生成素(FSH)、催乳素(PRL)、孕酮、雌二醇和睾酮的分析。禁欲72小时后通过手淫获取的精液样本进行精子计数和活力分析。结果显示,体重指数与孕酮和雌二醇的血清浓度以及精子计数之间在99%置信水平上存在统计学显著相关性。体重指数与精子活力、催乳素、睾酮和促黄体生成素的血清浓度之间未观察到显著相关性。总之,本研究表明体重指数、精液特征与男性性激素之间存在统计学显著相关性,可能会拓宽我们对男性生育/不育生理学的理解。

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