Pierrepoint C G, Jenkins B M, Wilson D W, Phillips M J, Gow J G
Fertil Steril. 1982 Oct;38(4):465-70. doi: 10.1016/s0015-0282(16)46582-9.
Plasma concentrations of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), testosterone (T), and 17 beta-estradiol (E2) have been measured in men complaining of infertility in comparison with men of proven fertility. Subgrouping of patients was achieved on the basis of the presence or absence of sperm in the ejaculate and further by the concentration of sperm or by testicular score. The levels of plasma LH, FSH, PRL, and T were found to be significantly different in the fertile men, compared with both infertile men with sperm in their ejaculates and azoospermic men. There were no significant differences between the groups for E2. There appeared to be an inverse relationship between LH concentrations and sperm count in both fertile and infertile men. FSH levels did not vary significantly in the fertile men in relation to sperm count grouping but were significantly less than those found for the infertile men with sperm. Azoospermic patients with high testicular scores had FSH levels indistinguishable from those of the fertile men. The results are discussed in terms of testicular abnormalities and on the interrelationship between the hormones examined.
对主诉不育的男性与已证实具有生育能力的男性进行了比较，测定了他们血浆中促黄体生成素（LH）、促卵泡激素（FSH）、催乳素（PRL）、睾酮（T）和17β-雌二醇（E2）的浓度。根据射精中是否存在精子对患者进行亚组划分，并进一步根据精子浓度或睾丸评分进行划分。结果发现，与射精中有精子的不育男性和无精子症男性相比，有生育能力的男性血浆中LH、FSH、PRL和T的水平存在显著差异。各组之间的E2水平没有显著差异。在有生育能力和不育的男性中，LH浓度与精子计数之间似乎呈负相关。在有生育能力的男性中，FSH水平在精子计数分组方面没有显著变化，但明显低于射精中有精子的不育男性。睾丸评分高的无精子症患者的FSH水平与有生育能力的男性无法区分。本文从睾丸异常以及所检测激素之间的相互关系方面对结果进行了讨论。
