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他汀类药物:我们是否已经找到了圣杯?

Statins: have we found the Holy Grail?

机构信息

University Hospital, Petersgraben 4, CH-4031 Basel, Switzerland.

出版信息

Swiss Med Wkly. 2012 Feb 3;142:w13515. doi: 10.4414/smw.2012.13515. eCollection 2012.

DOI:10.4414/smw.2012.13515
PMID:22315166
Abstract

In coronary artery disease, cardiovascular risk factors are the main targets for primary and secondary prevention. Statins prevent cardiovascular events in patients at risk. However, despite the proven efficacy and safety of statins, relevant side effects exist and should be considered when treating patients.

摘要

在冠状动脉疾病中,心血管风险因素是一级和二级预防的主要目标。他汀类药物可预防高危患者的心血管事件。然而,尽管他汀类药物已被证实具有疗效和安全性,但仍存在相关的副作用,在治疗患者时应予以考虑。

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Statins: have we found the Holy Grail?他汀类药物:我们是否已经找到了圣杯?
Swiss Med Wkly. 2012 Feb 3;142:w13515. doi: 10.4414/smw.2012.13515. eCollection 2012.
2
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What is the role of statins in the elderly population?他汀类药物在老年人群中的作用是什么?
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Update on statins and other lipid-lowering drugs.他汀类药物及其他降脂药物的最新进展
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Emerging clinical challenges in the use of statins.他汀类药物使用中出现的临床挑战。
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Statins in the elderly: what evidence of their benefit in prevention?老年人使用他汀类药物:其在预防方面有益的证据有哪些?
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Lipid modification and cardiovascular risk assessment for the primary and secondary prevention of cardiovascular disease: summary of updated NICE guidance.脂质修饰与心血管疾病一级和二级预防的心血管风险评估:英国国家卫生与临床优化研究所(NICE)最新指南总结
BMJ. 2014 Jul 17;349:g4356. doi: 10.1136/bmj.g4356.

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Subgingival Delivery of Statins as an Adjunct in the Non-Surgical Treatment of Periodontitis: A Systematic Review.他汀类药物龈下给药作为牙周炎非手术治疗辅助手段的系统评价
Biomedicines. 2025 Jan 13;13(1):182. doi: 10.3390/biomedicines13010182.
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The Use of Statins as an Adjunctive Periodontal Disease Treatment: Systematic Review and Meta-Analysis.他汀类药物作为牙周病辅助治疗的应用:系统评价与荟萃分析
Dent J (Basel). 2024 May 21;12(6):150. doi: 10.3390/dj12060150.
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The effect of statins on periodontal treatment-a systematic review with meta-analyses and meta-regression.
他汀类药物对牙周治疗效果的系统评价:荟萃分析和荟萃回归。
Clin Oral Investig. 2018 Mar;22(2):671-687. doi: 10.1007/s00784-018-2354-9. Epub 2018 Feb 2.
4
Comparative evaluation of efficacy of subgingivally delivered 1.2% Atorvastatin and 1.2% Simvastatin in the treatment of intrabony defects in chronic periodontitis: a randomized controlled trial.龈下给药1.2%阿托伐他汀和1.2%辛伐他汀治疗慢性牙周炎骨内缺损疗效的比较评估:一项随机对照试验。
J Dent Res Dent Clin Dent Prospects. 2017 Winter;11(1):18-25. doi: 10.15171/joddd.2017.004. Epub 2017 Mar 15.
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Circulating Thrombotic Risk Factors in Young Patients with Coronary Artery Disease Who Are on Statins and Anti-platelet Drugs.接受他汀类药物和抗血小板药物治疗的年轻冠心病患者的循环血栓形成危险因素
Indian J Clin Biochem. 2016 Jul;31(3):302-9. doi: 10.1007/s12291-015-0540-y. Epub 2015 Dec 22.
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Statins and cognitive decline in older adults with normal cognition or mild cognitive impairment.他汀类药物与认知正常或轻度认知障碍老年人的认知能力下降。
J Am Geriatr Soc. 2013 Sep;61(9):1449-55. doi: 10.1111/jgs.12414. Epub 2013 Sep 3.
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Chicken meat nutritional value when feeding red palm oil, palm oil or rendered animal fat in combinations with linseed oil, rapeseed oil and two levels of selenium.在喂养鸡肉时,用红花籽油、棕榈油或动物脂与亚麻籽油、菜籽油和两种硒水平组合,可以提高其营养价值。
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