Sagheb Mohammad Mahdi, Sharifian Maryam, Moini Maryam, Sharifian Amir Hossein
Nephrology Division, Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Trop Doct. 2012 Apr;42(2):90-1. doi: 10.1258/td.2011.110285. Epub 2012 Feb 8.
In this study we describe the clinical features of scorpion bites in southern Iran. The records of scorpion bite victims from January 2000 to January 2009 were obtained from the record library of the Shiraz Nemazi Hospital, Shiraz, Iran. A total of 232 scorpion bite patients were included. Only 14 patients (6%) developed systemic complications. Acute renal failure (ARF) and disseminated intravascular coagulation (DIC) were the most prevalent systemic complications. The renal toxicity of scorpion envenomation is mostly due to Hemiscorpius lepturus stings and this complication is more common in younger children. This may be due to a higher ratio of venom to body mass compared with adults. H. lepturus venom is naturally cytotoxic and may bind directly to kidney tissue causing tubular injury and inducing DIC and haemolysis.
在本研究中,我们描述了伊朗南部蝎子蜇伤的临床特征。2000年1月至2009年1月期间蝎子蜇伤受害者的记录来自伊朗设拉子内马齐医院的记录库。共纳入232例蝎子蜇伤患者。只有14例患者(6%)出现全身并发症。急性肾衰竭(ARF)和弥散性血管内凝血(DIC)是最常见的全身并发症。蝎子毒液的肾毒性主要归因于粗尾蝎蜇伤,这种并发症在年幼儿童中更常见。这可能是因为与成人相比,毒液与体重的比例更高。粗尾蝎毒液具有天然的细胞毒性,可能直接与肾组织结合,导致肾小管损伤,并引发DIC和溶血。