一系列因拔牙而就诊女性患者口服双膦酸盐治疗骨质疏松症的处方标准。
Criteria for the prescription of oral bisphosphonates for the treatment of osteoporosis in a series of women referred for tooth extraction.
机构信息
Oral Medicine and Oral Surgery Unit, Faculty of Medicine and Dentistry, University of Santiago de Compostela, Santiago de Compostela, Spain.
出版信息
Med Oral Patol Oral Cir Bucal. 2012 Jul 1;17(4):e601-4. doi: 10.4317/medoral.17681.
OBJECTIVE
To evaluate the criteria for the prescription of oral bisphosphonates (OB) in a series of women with osteoporosis referred for tooth extraction.
STUDY DESIGN
The study included 38 postmenopausal women on treatment with OBs. The following variables were analysed: age, weight, height, type of OB and duration of treatment, bone densitometry and risk factors for osteoporosis. In addition, the osteoporosis self-assessment tool (OST) was administered and collagen type I C-telopeptide (CTX) levels were measured.
RESULTS
Bone densitometry had only been performed in six patients (15.7%) before starting OB treatment. Based on the results of the OST, nine (23.6%) of the participants presented a low risk of osteoporosis. CTX levels were measured in 23 patients: 11 (47.8%) presented values below 150 pg/ml.
CONCLUSION
Although all patients in the present series were on treatment with OBs, a large percentage did not satisfy the criteria for the initiation of treatment for postmenopausal osteoporosis.
目的
评估一系列因拔牙而转诊的骨质疏松女性患者开具口服双膦酸盐（OB）处方的标准。
研究设计
本研究纳入了 38 名正在接受 OB 治疗的绝经后妇女。分析了以下变量：年龄、体重、身高、OB 类型和治疗持续时间、骨密度和骨质疏松危险因素。此外，还进行了骨质疏松自我评估工具（OST）评估和 I 型胶原 C 端肽（CTX）水平测定。
结果
在开始 OB 治疗之前，仅有 6 名患者（15.7%）进行了骨密度检查。根据 OST 的结果，9 名（23.6%）参与者骨质疏松风险较低。对 23 名患者进行了 CTX 水平测定：11 名（47.8%）患者的 CTX 值低于 150pg/ml。
结论
尽管本研究系列中的所有患者均接受 OB 治疗，但很大一部分患者不符合绝经后骨质疏松症起始治疗的标准。
Zotero 插件