Kioka Y, Pego-Fernandes P M, Pomerantzeff P M, Jatene A D
Heart Institute of São Paulo University Medical School.
Kyobu Geka. 1990 Aug;43(9):718-23.
From January/1983 to March/1988, 28 patients were submitted to valve replacements for prosthetic valve endocarditis in 1,512 valve replacements. Seventeen patients were male, their mean age was 36.7 +/- 12.9 years old, and eight cases were operated under emergency condition. The blood cultures were positive in 14 (50%), the agent most commonly found being Streptococcus viridans in 5 cases. Hospital mortality was 28.5%. The causes of death were septicemia in 4 cases, low output syndrome in 2 cases, cerebrovascular accident in 1 case, and coagulopathy in 1 case. Mortality was higher with statistical significance in the cases whose blood cultures were negative, the cases in which the time from valve replacement to the onset of endocarditis was less than one year, and the cases under emergency condition.
从1983年1月至1988年3月，在1512例瓣膜置换手术中，有28例患者因人工瓣膜心内膜炎接受了瓣膜置换术。17例为男性，平均年龄为36.7±12.9岁，8例在紧急情况下接受手术。血培养阳性者14例（50%），最常见的病原体是草绿色链球菌，共5例。医院死亡率为28.5%。死亡原因包括败血症4例、低心排血量综合征2例、脑血管意外1例、凝血病1例。血培养阴性的病例、瓣膜置换至心内膜炎发病时间少于一年的病例以及紧急情况下的病例，死亡率较高，具有统计学意义。
