A novel hemodynamic observation: worsening of tricuspid regurgitation with dobutamine infusion during a hemodynamic study.

Dobutamine has been shown to improve right ventricular contractility and cardiac output in right ventricular failure. However, the effect of dobutamine in the select group of patients with severe tricuspid regurgitation (TR) has not been described previously. We report the case of a patient with severe TR and right heart failure who developed ventricularization of right atrial pressure after dobutamine infusion. This highlights the potential worsening of TR and right heart failure in patients with TR receiving dobutamine.