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患有物质滥用障碍的全髋关节置换术患者出现急性意识错乱和治疗依从性差。

Acute delirium and poor compliance in total hip arthroplasty patients with substance abuse disorders.

机构信息

Department of Orthopedic Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

出版信息

J Arthroplasty. 2012 Sep;27(8):1526-9. doi: 10.1016/j.arth.2011.12.003. Epub 2012 Feb 8.

DOI:10.1016/j.arth.2011.12.003
PMID:22325962
Abstract

From the joint registry of 2831 primary total hip arthroplasties (2351 patients) performed between 1998 and 2003, we identified 15 patients (16 hips) who had a documented history of substance abuse disorders at the time of the index surgery. The patients included 13 men (14 hips) and 2 women (2 hips), with the mean age of 49 years (range, 29-65 years). On the basis of the criteria specified in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, 13 patients had alcohol abuse disorders, 1 had amphetamine abuse disorder, and 1 had heroin abuse disorder. We found high rates of postoperative substance withdrawal delirium and psychosis (46%), late complication (25%), and lost to follow-up (27%) in these patients. Because patients with substance abuse disorders have unexpected perioperative psychotic episodes, poor compliance, and a tendency to not follow medical advice after surgery and show early discontinuation of follow-up, we suggest that surgeons should work with other medical professionals and carefully perform total hip arthroplasty in such patients.

摘要

从 1998 年至 2003 年进行的 2831 例初次全髋关节置换术(2351 例患者)的联合注册中心中,我们确定了 15 例(16 髋)在指数手术时存在药物滥用障碍病史的患者。这些患者包括 13 名男性(14 髋)和 2 名女性(2 髋),平均年龄为 49 岁(范围为 29-65 岁)。根据《精神障碍诊断与统计手册》第四版的规定,13 名患者患有酒精滥用障碍,1 名患者患有安非他命滥用障碍,1 名患者患有海洛因滥用障碍。我们发现这些患者术后物质戒断谵妄和精神病的发生率很高(46%),晚期并发症(25%)和失访(27%)。由于患有药物滥用障碍的患者在围手术期会出现意外的精神病发作、不遵守医嘱和术后不遵循医疗建议的倾向,并且早期停止随访,因此我们建议外科医生应与其他医疗专业人员合作,在这些患者中仔细进行全髋关节置换术。

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