Orthopaedic Department, Hospital Universitario De Canarias, La Laguna, Tenerife, Canary Islands, Spain.
Foot Ankle Surg. 2012 Mar;18(1):e18-20. doi: 10.1016/j.fas.2011.10.008. Epub 2011 Nov 18.
Malignant melanoma is not a common cause of cancer metastasis to the skeleton, however, when melanoma does metastasize, one of the most common sites is the skeleton. In the literature, there are very few reports of bone metastasis and bone fracture from malignant melanoma, but they do clearly occur. When skeletal metastasis from malignant melanoma occurs, it is a sign of a very serious stage of the disease. We here present a case of a 39-year-old man with a history of ankle pain since an ankle sprain two months before, who was remitted to our unit with the diagnosis of pathological fracture of the distal tibia secondary to disseminated melanoma.
恶性黑素瘤并非癌症骨骼转移的常见原因，然而，当黑素瘤确实发生转移时，最常见的部位之一是骨骼。在文献中，恶性黑素瘤引起骨转移和骨折的报道非常少，但确实会发生。当恶性黑素瘤发生骨骼转移时，这是疾病非常严重阶段的一个迹象。我们在此介绍一例 39 岁男性病例，该患者两个月前踝关节扭伤后出现踝关节疼痛，因播散性黑素瘤继发的胫骨远端病理性骨折转入我科。
